LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 1188 | 5578 | 0.2131 | -0.4464 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4140 | 5578 | 0.7421 | 0.5260 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4380 | 5578 | 0.7853 | 0.6053 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5952 | 5578 | 1.0670 | 1.1232 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4005 | 5578 | 0.7180 | 0.4816 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1713 | 5578 | 0.3071 | -0.2735 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4912 | 5578 | 0.8805 | 0.7804 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 905 | 5578 | 0.1623 | -0.5397 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2056 | 5578 | 0.3686 | -0.1605 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 3259 | 5578 | 0.5842 | 0.2358 |
| SK-BR-3 | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5751 | 5578 | 1.0310 | 1.0570 |
| SK-BR-3 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1559 | 5578 | 0.2795 | -0.3242 |
| SK-BR-3 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1782 | 5578 | 0.3196 | -0.2507 |
| SK-BR-3 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4742 | 5578 | 0.8500 | 0.7244 |
| SK-BR-3 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2071 | 5578 | 0.3712 | -0.1557 |
| SK-BR-3 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1517 | 5578 | 0.2721 | -0.3380 |
| SK-BR-3 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 5050 | 5578 | 0.9052 | 0.8258 |
| SK-BR-3 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1260 | 5578 | 0.2259 | -0.4229 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2123 | 5578 | 0.3806 | -0.1385 |
| SK-BR-3 | NVP-AEW541 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5650 | 5578 | 1.0129 | 1.0237 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6254 | 5578 | 1.1211 | 1.2225 |
| SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 6002 | 5578 | 1.0759 | 1.1395 |
| SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4779 | 5578 | 0.8567 | 0.7365 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4719 | 5578 | 0.8460 | 0.7170 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2194 | 5578 | 0.3933 | -0.1151 |