LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 566 | 5667 | 0.0999 | -0.1924 |
| MCF7 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1046 | 5667 | 0.1846 | -0.0801 |
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 343 | 5667 | 0.0605 | -0.2445 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 300 | 5667 | 0.0530 | -0.2544 |
| MCF7 | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2034 | 5667 | 0.3590 | 0.1509 |
| MCF7 | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 3532 | 5667 | 0.6233 | 0.5009 |
| MCF7 | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 5776 | 5667 | 1.0192 | 1.0254 |
| MCF7 | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1079 | 5667 | 0.1904 | -0.0725 |
| MCF7 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1687 | 5667 | 0.2977 | 0.0697 |
| MCF7 | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1168 | 5667 | 0.2061 | -0.0517 |
| MCF7 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 832 | 5667 | 0.1468 | -0.1302 |
| MCF7 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 2573 | 5667 | 0.4540 | 0.2767 |
| MCF7 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1389 | 6072 | 5667 | 1.0714 | 1.0946 |
| MCF7 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 5477 | 5667 | 0.9663 | 0.9554 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1389 | 782 | 5667 | 0.1380 | -0.1419 |
| MCF7 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2309 | 5667 | 0.4074 | 0.2150 |
| MCF7 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1215 | 5667 | 0.2145 | -0.0405 |
| MCF7 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 4654 | 5667 | 0.8211 | 0.7630 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1389 | 699 | 5667 | 0.1234 | -0.1612 |
| MCF7 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1389 | 621 | 5667 | 0.1097 | -0.1794 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 1167 | 5667 | 0.2059 | -0.0519 |
| MCF7 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1389 | 1060 | 5667 | 0.1871 | -0.0768 |
| MCF7 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1389 | 2699 | 5667 | 0.4762 | 0.3061 |
| MCF7 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1389 | 746 | 5667 | 0.1316 | -0.1503 |
| MCF7 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1389 | 2689 | 5667 | 0.4745 | 0.3039 |