LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 513 | 593 | 10401 | 0.0570 | 0.0081 |
| MCF 10A | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 513 | 778 | 10401 | 0.0748 | 0.0268 |
| MCF 10A | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 513 | 2029 | 10401 | 0.1951 | 0.1533 |
| MCF 10A | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 513 | 543 | 10401 | 0.0522 | 0.0030 |
| MCF 10A | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 513 | 7238 | 10401 | 0.6960 | 0.6802 |
| MCF 10A | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 513 | 732 | 10401 | 0.0704 | 0.0221 |
| MCF 10A | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 513 | 4879 | 10401 | 0.4691 | 0.4415 |
| MCF 10A | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 513 | 3369 | 10401 | 0.3239 | 0.2888 |
| MCF 10A | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10904 | 10401 | 1.0483 | 1.0509 |
| MCF 10A | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 513 | 783 | 10401 | 0.0753 | 0.0273 |
| MCF 10A | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 513 | 6953 | 10401 | 0.6686 | 0.6513 |
| MCF 10A | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 6980 | 10401 | 0.6711 | 0.6540 |
| MCF 10A | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 513 | 8625 | 10401 | 0.8292 | 0.8204 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10826 | 10401 | 1.0408 | 1.0430 |
| MCF 10A | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 3861 | 10401 | 0.3713 | 0.3386 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 513 | 387 | 10401 | 0.0372 | -0.0128 |
| MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 513 | 458 | 10401 | 0.0441 | -0.0056 |
| MCF 10A | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 513 | 7275 | 10401 | 0.6994 | 0.6838 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 712 | 10401 | 0.0685 | 0.0201 |
| MCF 10A | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 10885 | 10401 | 1.0465 | 1.0489 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10459 | 10401 | 1.0056 | 1.0059 |
| MCF 10A | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 513 | 9249 | 10401 | 0.8892 | 0.8835 |
| MCF 10A | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 513 | 991 | 10401 | 0.0953 | 0.0483 |
| MCF 10A | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 513 | 2398 | 10401 | 0.2306 | 0.1906 |
| MCF 10A | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 513 | 3769 | 10401 | 0.3624 | 0.3293 |