LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Canertinib
0.12
uM
LJP6
 72
hr
 513 1120 10401 0.1077 0.0614
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 513 11759 10401 1.1306 1.1374
MCF 10A CGP60474
0.12
uM
LJP5
 72
hr
 513 677 10401 0.0651 0.0165
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 513 550 10401 0.0529 0.0038
MCF 10A CHIR-99021
0.12
uM
LJP6
 72
hr
 513 9570 10401 0.9202 0.9160
MCF 10A CP724714
0.12
uM
LJP5
 72
hr
 513 10313 10401 0.9916 0.9911
MCF 10A CP466722
0.12
uM
LJP5
 72
hr
 513 10964 10401 1.0541 1.0570
MCF 10A Crizotinib
0.12
uM
LJP5
 72
hr
 513 8949 10401 0.8605 0.8532
MCF 10A Momelotinib
0.12
uM
LJP5
 72
hr
 513 8077 10401 0.7766 0.7650
MCF 10A Dasatinib
0.12
uM
LJP5
 72
hr
 513 1768 10401 0.1700 0.1269
MCF 10A Dasatinib
0.12
uM
LJP6
 72
hr
 513 741 10401 0.0713 0.0231
MCF 10A Dovitinib
0.12
uM
LJP5
 72
hr
 513 7328 10401 0.7046 0.6892
MCF 10A Enzastaurin
0.12
uM
LJP5
 72
hr
 513 10051 10401 0.9664 0.9646
MCF 10A Erlotinib
0.12
uM
LJP5
 72
hr
 513 8611 10401 0.8280 0.8190
MCF 10A Foretinib
0.12
uM
LJP5
 72
hr
 513 10269 10401 0.9873 0.9866
MCF 10A R406
0.12
uM
LJP6
 72
hr
 513 9549 10401 0.9181 0.9138
MCF 10A Pictilisib
0.12
uM
LJP6
 72
hr
 513 3776 10401 0.3630 0.3300
MCF 10A Gefitinib
0.12
uM
LJP6
 72
hr
 513 2719 10401 0.2615 0.2231
MCF 10A Geldanamycin
0.12
uM
LJP5
 72
hr
 513 528 10401 0.0508 0.0015
MCF 10A Geldanamycin
0.12
uM
LJP6
 72
hr
 513 554 10401 0.0533 0.0041
MCF 10A GSK1059615
0.12
uM
LJP5
 72
hr
 513 7518 10401 0.7228 0.7084
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 513 5019 10401 0.4825 0.4557
MCF 10A GSK1904529A
0.12
uM
LJP6
 72
hr
 513 3050 10401 0.2932 0.2565
MCF 10A Omipalisib
0.12
uM
LJP6
 72
hr
 513 607 10401 0.0584 0.0095
MCF 10A GSK 690693
0.12
uM
LJP5
 72
hr
 513 9574 10401 0.9205 0.9164