LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 513 8086 10401 0.7775 0.7659
MCF 10A AZD7762
0.12
uM
LJP6
 72
hr
 513 4519 10401 0.4345 0.4051
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 513 1215 10401 0.1168 0.0710
MCF 10A AZD8330
0.12
uM
LJP5
 72
hr
 513 487 10401 0.0469 -0.0026
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 513 1333 10401 0.1282 0.0829
MCF 10A BI-2536
0.12
uM
LJP6
 72
hr
 513 846 10401 0.0813 0.0336
MCF 10A BMS345541
0.12
uM
LJP6
 72
hr
 513 10353 10401 0.9954 0.9952
MCF 10A SNS-032
0.12
uM
LJP6
 72
hr
 513 662 10401 0.0637 0.0151
MCF 10A GDC-0980
0.12
uM
LJP5
 72
hr
 513 2441 10401 0.2347 0.1950
MCF 10A NVP-AEW541
0.12
uM
LJP5
 72
hr
 513 8816 10401 0.8476 0.8397
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 513 10715 10401 1.0302 1.0317
MCF 10A PIK-93
0.12
uM
LJP5
 72
hr
 513 10421 10401 1.0020 1.0021
MCF 10A KIN001-043
0.12
uM
LJP6
 72
hr
 513 10587 10401 1.0179 1.0188
MCF 10A Alpelisib
0.12
uM
LJP5
 72
hr
 513 8470 10401 0.8143 0.8047
MCF 10A Luminespib
0.12
uM
LJP5
 72
hr
 513 495 10401 0.0476 -0.0018
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 513 2023 10401 0.1946 0.1527
MCF 10A OSI-027
0.12
uM
LJP6
 72
hr
 513 3642 10401 0.3502 0.3164
MCF 10A XMD11-85h
0.12
uM
LJP6
 72
hr
 513 8939 10401 0.8594 0.8521
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 513 10535 10401 1.0129 1.0136
MCF 10A WH-4-025
0.12
uM
LJP5
 72
hr
 513 7014 10401 0.6744 0.6575
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 513 9065 10401 0.8715 0.8649
MCF 10A XMD16-144
0.12
uM
LJP5
 72
hr
 513 2848 10401 0.2739 0.2362
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 513 9366 10401 0.9005 0.8953
MCF 10A Buparlisib
0.12
uM
LJP5
 72
hr
 513 8404 10401 0.8080 0.7981
MCF 10A BX-912
0.12
uM
LJP5
 72
hr
 513 9452 10401 0.9088 0.9041