LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1825 | 3228 | 0.5656 | 0.3900 |
Hs 578T | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1146 | 3228 | 0.3550 | 0.0943 |
Hs 578T | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 929 | 995 | 3228 | 0.3083 | 0.0287 |
Hs 578T | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 929 | 1367 | 3228 | 0.4235 | 0.1904 |
Hs 578T | Trametinib | 3.33 | uM | LJP5 | 72 | hr | 929 | 1419 | 3228 | 0.4396 | 0.2131 |
Hs 578T | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 929 | 2570 | 3228 | 0.7964 | 0.7140 |
Hs 578T | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 929 | 2962 | 3228 | 0.9176 | 0.8843 |
Hs 578T | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 929 | 827 | 3228 | 0.2563 | -0.0443 |
Hs 578T | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 929 | 732 | 3228 | 0.2270 | -0.0855 |
Hs 578T | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1331 | 3228 | 0.4124 | 0.1749 |
Hs 578T | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 929 | 839 | 3228 | 0.2600 | -0.0391 |
Hs 578T | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1644 | 3228 | 0.5094 | 0.3111 |
Hs 578T | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 929 | 2102 | 3228 | 0.6512 | 0.5102 |
Hs 578T | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 929 | 2396 | 3228 | 0.7423 | 0.6382 |
Hs 578T | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1457 | 3228 | 0.4515 | 0.2297 |
Hs 578T | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 929 | 736 | 3228 | 0.2281 | -0.0839 |
Hs 578T | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 929 | 1741 | 3228 | 0.5395 | 0.3534 |
Hs 578T | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 929 | 814 | 3228 | 0.2523 | -0.0500 |
Hs 578T | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 929 | 616 | 3228 | 0.1910 | -0.1360 |
Hs 578T | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 929 | 786 | 3228 | 0.2437 | -0.0620 |
Hs 578T | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 929 | 1568 | 3228 | 0.4857 | 0.2779 |
Hs 578T | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 929 | 715 | 3228 | 0.2216 | -0.0931 |
Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 929 | 1012 | 3228 | 0.3136 | 0.0361 |
Hs 578T | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 929 | 1511 | 3228 | 0.4681 | 0.2531 |
Hs 578T | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 929 | 1442 | 3228 | 0.4467 | 0.2231 |