LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PF431396
0.37
uM
LJP5
 72
hr
 929 2177 3228 0.6746 0.5431
Hs 578T PF477736
0.37
uM
LJP5
 72
hr
 929 1377 3228 0.4267 0.1949
Hs 578T PF562271
0.37
uM
LJP6
 72
hr
 929 2472 3228 0.7658 0.6711
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 929 3263 3228 1.0109 1.0153
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 929 1593 3228 0.4936 0.2889
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 929 1354 3228 0.4197 0.1851
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 929 3703 3228 1.1472 1.2067
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 929 2212 3228 0.6855 0.5583
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 929 2623 3228 0.8127 0.7369
Hs 578T Radicicol
0.37
uM
LJP5
 72
hr
 929 3180 3228 0.9851 0.9791
Hs 578T Radicicol
0.37
uM
LJP6
 72
hr
 929 3006 3228 0.9313 0.9036
Hs 578T Seliciclib
0.37
uM
LJP5
 72
hr
 929 3143 3228 0.9738 0.9631
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 929 3162 3228 0.9795 0.9713
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 929 3202 3228 0.9920 0.9888
Hs 578T Saracatinib
0.37
uM
LJP6
 72
hr
 929 2606 3228 0.8074 0.7295
Hs 578T Selumetinib
0.37
uM
LJP6
 72
hr
 929 1748 3228 0.5415 0.3562
Hs 578T Sirolimus
0.37
uM
LJP6
 72
hr
 929 2179 3228 0.6751 0.5438
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 929 3923 3228 1.2155 1.3026
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 929 3089 3228 0.9569 0.9395
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 929 2959 3228 0.9169 0.8833
Hs 578T TGX221
0.37
uM
LJP5
 72
hr
 929 2964 3228 0.9183 0.8853
Hs 578T Torin1
0.37
uM
LJP6
 72
hr
 929 1314 3228 0.4072 0.1675
Hs 578T Torin2
0.37
uM
LJP5
 72
hr
 929 1130 3228 0.3502 0.0875
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 929 1386 3228 0.4294 0.1987
Hs 578T Trametinib
0.37
uM
LJP5
 72
hr
 929 1485 3228 0.4600 0.2418