LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 929 3051 3228 0.9452 0.9230
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 929 3193 3228 0.9892 0.9848
Hs 578T LDN-193189
0.04
uM
LJP5
 72
hr
 929 3117 3228 0.9657 0.9518
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 929 3168 3228 0.9814 0.9739
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 929 3174 3228 0.9834 0.9766
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 929 1292 3228 0.4003 0.1580
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 929 1329 3228 0.4117 0.1739
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 929 2927 3228 0.9067 0.8690
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 929 2920 3228 0.9047 0.8661
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 929 3632 3228 1.1253 1.1760
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 929 2947 3228 0.9131 0.8780
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 929 3193 3228 0.9893 0.9850
Hs 578T Dactolisib
0.04
uM
LJP5
 72
hr
 929 1562 3228 0.4841 0.2755
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 929 2877 3228 0.8915 0.8476
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 929 2313 3228 0.7165 0.6019
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 929 1821 3228 0.5642 0.3881
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 929 1786 3228 0.5534 0.3728
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 929 2861 3228 0.8865 0.8406
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 929 2483 3228 0.7692 0.6759
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 929 3215 3228 0.9961 0.9945
Hs 578T PF431396
0.04
uM
LJP5
 72
hr
 929 2578 3228 0.7987 0.7174
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 929 3161 3228 0.9793 0.9710
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 929 2878 3228 0.8918 0.8480
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 929 3287 3228 1.0185 1.0259
Hs 578T PHA-793887
0.04
uM
LJP6
 72
hr
 929 2039 3228 0.6319 0.4830