LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3174 | 3228 | 0.9835 | 0.9768 |
Hs 578T | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3355 | 3228 | 1.0394 | 1.0554 |
Hs 578T | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 3151 | 3228 | 0.9761 | 0.9665 |
Hs 578T | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 2939 | 3228 | 0.9106 | 0.8744 |
Hs 578T | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 2282 | 3228 | 0.7070 | 0.5886 |
Hs 578T | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 929 | 1528 | 3228 | 0.4735 | 0.2606 |
Hs 578T | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 2551 | 3228 | 0.7904 | 0.7056 |
Hs 578T | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 929 | 3281 | 3228 | 1.0165 | 1.0232 |
Hs 578T | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 3145 | 3228 | 0.9745 | 0.9642 |
Hs 578T | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 929 | 3046 | 3228 | 0.9438 | 0.9211 |
Hs 578T | R406 | 0.04 | uM | LJP6 | 72 | hr | 929 | 3133 | 3228 | 0.9708 | 0.9589 |
Hs 578T | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 929 | 2559 | 3228 | 0.7927 | 0.7090 |
Hs 578T | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 929 | 3235 | 3228 | 1.0021 | 1.0030 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 929 | 2552 | 3228 | 0.7908 | 0.7062 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 929 | 2701 | 3228 | 0.8368 | 0.7709 |
Hs 578T | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3168 | 3228 | 0.9816 | 0.9742 |
Hs 578T | GSK1059615 | 0.04 | uM | LJP6 | 72 | hr | 929 | 2974 | 3228 | 0.9213 | 0.8895 |
Hs 578T | GSK1904529A | 0.04 | uM | LJP6 | 72 | hr | 929 | 3169 | 3228 | 0.9817 | 0.9743 |
Hs 578T | Omipalisib | 0.04 | uM | LJP6 | 72 | hr | 929 | 1409 | 3228 | 0.4366 | 0.2088 |
Hs 578T | GSK 690693 | 0.04 | uM | LJP5 | 72 | hr | 929 | 2630 | 3228 | 0.8149 | 0.7401 |
Hs 578T | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 929 | 3236 | 3228 | 1.0027 | 1.0037 |
Hs 578T | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3070 | 3228 | 0.9512 | 0.9315 |
Hs 578T | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 929 | 3095 | 3228 | 0.9588 | 0.9421 |
Hs 578T | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 929 | 3231 | 3228 | 1.0009 | 1.0013 |
Hs 578T | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 929 | 3333 | 3228 | 1.0325 | 1.0456 |