LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PI103
0.04
uM
LJP6
 72
hr
 929 2243 3228 0.6950 0.5716
Hs 578T PLX-4720
0.04
uM
LJP5
 72
hr
 929 3436 3228 1.0645 1.0906
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 929 2741 3228 0.8492 0.7883
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 929 3047 3228 0.9441 0.9215
Hs 578T Radicicol
0.04
uM
LJP5
 72
hr
 929 3370 3228 1.0442 1.0620
Hs 578T Radicicol
0.04
uM
LJP6
 72
hr
 929 3330 3228 1.0316 1.0443
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 929 3284 3228 1.0174 1.0245
Hs 578T Ruxolitinib
0.04
uM
LJP5
 72
hr
 929 3198 3228 0.9908 0.9871
Hs 578T XL147
0.04
uM
LJP5
 72
hr
 929 3301 3228 1.0227 1.0319
Hs 578T Saracatinib
0.04
uM
LJP6
 72
hr
 929 3166 3228 0.9810 0.9733
Hs 578T Selumetinib
0.04
uM
LJP6
 72
hr
 929 2018 3228 0.6251 0.4736
Hs 578T Sirolimus
0.04
uM
LJP6
 72
hr
 929 2228 3228 0.6904 0.5653
Hs 578T Sorafenib
0.04
uM
LJP6
 72
hr
 929 3783 3228 1.1720 1.2415
Hs 578T SU11274
0.04
uM
LJP5
 72
hr
 929 3333 3228 1.0327 1.0459
Hs 578T Fedratinib
0.04
uM
LJP5
 72
hr
 929 3318 3228 1.0281 1.0394
Hs 578T TGX221
0.04
uM
LJP5
 72
hr
 929 3021 3228 0.9359 0.9099
Hs 578T Torin1
0.04
uM
LJP6
 72
hr
 929 1429 3228 0.4429 0.2177
Hs 578T Torin2
0.04
uM
LJP5
 72
hr
 929 1403 3228 0.4347 0.2062
Hs 578T Tozasertib
0.04
uM
LJP5
 72
hr
 929 1399 3228 0.4334 0.2044
Hs 578T Trametinib
0.04
uM
LJP5
 72
hr
 929 1525 3228 0.4726 0.2595
Hs 578T TWS119
0.04
uM
LJP5
 72
hr
 929 3301 3228 1.0226 1.0317
Hs 578T Vemurafenib
0.04
uM
LJP5
 72
hr
 929 3317 3228 1.0276 1.0387
Hs 578T Withaferin A
0.04
uM
LJP5
 72
hr
 929 3227 3228 0.9997 0.9995
Hs 578T Withaferin A
0.04
uM
LJP6
 72
hr
 929 3234 3228 1.0020 1.0029
Hs 578T WYE-125132
0.04
uM
LJP6
 72
hr
 929 1422 3228 0.4407 0.2146