LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T TWS119
0.37
uM
LJP5
 72
hr
 929 3175 3228 0.9838 0.9772
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 929 3434 3228 1.0640 1.0899
Hs 578T Withaferin A
0.37
uM
LJP5
 72
hr
 929 3324 3228 1.0298 1.0419
Hs 578T Withaferin A
0.37
uM
LJP6
 72
hr
 929 3294 3228 1.0206 1.0290
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 929 1338 3228 0.4147 0.1781
Hs 578T WZ3105
0.37
uM
LJP5
 72
hr
 929 866 3228 0.2685 -0.0272
Hs 578T XMD11-50
0.37
uM
LJP6
 72
hr
 929 2719 3228 0.8423 0.7786
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 929 2606 3228 0.8075 0.7297
Hs 578T YM 201636
0.37
uM
LJP5
 72
hr
 929 3251 3228 1.0072 1.0101
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 929 1832 3228 0.5675 0.3927
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 929 2985 3228 0.9249 0.8946
Hs 578T Sigma A6730
1.11
uM
LJP5
 72
hr
 929 2906 3228 0.9004 0.8602
Hs 578T Alvocidib
1.11
uM
LJP6
 72
hr
 929 764 3228 0.2368 -0.0717
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 929 868 3228 0.2689 -0.0266
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 929 1009 3228 0.3128 0.0350
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 929 2562 3228 0.7938 0.7104
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 929 1015 3228 0.3146 0.0376
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 929 1254 3228 0.3887 0.1416
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 929 1571 3228 0.4868 0.2793
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 929 1851 3228 0.5734 0.4010
Hs 578T BI-2536
1.11
uM
LJP6
 72
hr
 929 982 3228 0.3042 0.0229
Hs 578T BMS345541
1.11
uM
LJP6
 72
hr
 929 3115 3228 0.9650 0.9508
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 929 769 3228 0.2382 -0.0697
Hs 578T GDC-0980
1.11
uM
LJP5
 72
hr
 929 1341 3228 0.4154 0.1791
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 929 3290 3228 1.0192 1.0269