LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T BI-2536
10.0
uM
LJP6
 72
hr
 929 991 3228 0.3072 0.0272
Hs 578T BMS345541
10.0
uM
LJP6
 72
hr
 929 804 3228 0.2493 -0.0542
Hs 578T SNS-032
10.0
uM
LJP6
 72
hr
 929 800 3228 0.2478 -0.0562
Hs 578T GDC-0980
10.0
uM
LJP5
 72
hr
 929 1198 3228 0.3712 0.1171
Hs 578T NVP-AEW541
10.0
uM
LJP5
 72
hr
 929 1693 3228 0.5246 0.3324
Hs 578T SB590885
10.0
uM
LJP5
 72
hr
 929 2977 3228 0.9222 0.8908
Hs 578T PIK-93
10.0
uM
LJP5
 72
hr
 929 1354 3228 0.4197 0.1851
Hs 578T KIN001-043
10.0
uM
LJP6
 72
hr
 929 1794 3228 0.5558 0.3762
Hs 578T Alpelisib
10.0
uM
LJP5
 72
hr
 929 2115 3228 0.6553 0.5160
Hs 578T Luminespib
10.0
uM
LJP5
 72
hr
 929 1302 3228 0.4034 0.1623
Hs 578T A443654
10.0
uM
LJP6
 72
hr
 929 684 3228 0.2119 -0.1067
Hs 578T OSI-027
10.0
uM
LJP6
 72
hr
 929 1356 3228 0.4201 0.1856
Hs 578T XMD11-85h
10.0
uM
LJP6
 72
hr
 929 1611 3228 0.4991 0.2966
Hs 578T HG-6-64-01
10.0
uM
LJP6
 72
hr
 929 682 3228 0.2114 -0.1074
Hs 578T WH-4-025
10.0
uM
LJP5
 72
hr
 929 617 3228 0.1912 -0.1357
Hs 578T WZ-4-145
10.0
uM
LJP6
 72
hr
 929 1275 3228 0.3952 0.1507
Hs 578T XMD16-144
10.0
uM
LJP5
 72
hr
 929 832 3228 0.2577 -0.0423
Hs 578T Brivanib
10.0
uM
LJP5
 72
hr
 929 2759 3228 0.8548 0.7961
Hs 578T Buparlisib
10.0
uM
LJP5
 72
hr
 929 657 3228 0.2036 -0.1183
Hs 578T BX-912
10.0
uM
LJP5
 72
hr
 929 934 3228 0.2895 0.0024
Hs 578T Canertinib
10.0
uM
LJP6
 72
hr
 929 609 3228 0.1889 -0.1390
Hs 578T Celastrol
10.0
uM
LJP6
 72
hr
 929 564 3228 0.1749 -0.1586
Hs 578T CGP60474
10.0
uM
LJP5
 72
hr
 929 788 3228 0.2441 -0.0614
Hs 578T CGP60474
10.0
uM
LJP6
 72
hr
 929 669 3228 0.2074 -0.1131
Hs 578T CHIR-99021
10.0
uM
LJP6
 72
hr
 929 1986 3228 0.6152 0.4597