LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T SB590885
1.11
uM
LJP5
 72
hr
 929 3899 3228 1.2079 1.2920
Hs 578T PIK-93
1.11
uM
LJP5
 72
hr
 929 3280 3228 1.0161 1.0226
Hs 578T KIN001-043
1.11
uM
LJP6
 72
hr
 929 3310 3228 1.0254 1.0356
Hs 578T Alpelisib
1.11
uM
LJP5
 72
hr
 929 2851 3228 0.8834 0.8363
Hs 578T Luminespib
1.11
uM
LJP5
 72
hr
 929 1358 3228 0.4208 0.1867
Hs 578T A443654
1.11
uM
LJP6
 72
hr
 929 719 3228 0.2227 -0.0915
Hs 578T OSI-027
1.11
uM
LJP6
 72
hr
 929 1713 3228 0.5309 0.3412
Hs 578T XMD11-85h
1.11
uM
LJP6
 72
hr
 929 2949 3228 0.9137 0.8788
Hs 578T HG-6-64-01
1.11
uM
LJP6
 72
hr
 929 1887 3228 0.5846 0.4166
Hs 578T WH-4-025
1.11
uM
LJP5
 72
hr
 929 1213 3228 0.3758 0.1234
Hs 578T WZ-4-145
1.11
uM
LJP6
 72
hr
 929 1990 3228 0.6167 0.4617
Hs 578T XMD16-144
1.11
uM
LJP5
 72
hr
 929 1318 3228 0.4083 0.1691
Hs 578T Brivanib
1.11
uM
LJP5
 72
hr
 929 3039 3228 0.9414 0.9178
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 929 1390 3228 0.4308 0.2007
Hs 578T BX-912
1.11
uM
LJP5
 72
hr
 929 1708 3228 0.5291 0.3388
Hs 578T Canertinib
1.11
uM
LJP6
 72
hr
 929 3025 3228 0.9373 0.9120
Hs 578T Celastrol
1.11
uM
LJP6
 72
hr
 929 1268 3228 0.3928 0.1474
Hs 578T CGP60474
1.11
uM
LJP5
 72
hr
 929 837 3228 0.2593 -0.0401
Hs 578T CGP60474
1.11
uM
LJP6
 72
hr
 929 780 3228 0.2416 -0.0649
Hs 578T CHIR-99021
1.11
uM
LJP6
 72
hr
 929 2926 3228 0.9064 0.8686
Hs 578T CP724714
1.11
uM
LJP5
 72
hr
 929 3139 3228 0.9724 0.9613
Hs 578T CP466722
1.11
uM
LJP5
 72
hr
 929 3402 3228 1.0539 1.0757
Hs 578T Crizotinib
1.11
uM
LJP5
 72
hr
 929 2815 3228 0.8720 0.8203
Hs 578T Momelotinib
1.11
uM
LJP5
 72
hr
 929 2307 3228 0.7148 0.5995
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 929 1283 3228 0.3976 0.1540