LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 929 888 3228 0.2751 -0.0179
Hs 578T XMD11-50
0.04
uM
LJP6
 72
hr
 929 3165 3228 0.9806 0.9727
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 929 2906 3228 0.9002 0.8599
Hs 578T YM 201636
0.04
uM
LJP5
 72
hr
 929 3387 3228 1.0492 1.0691
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 929 2659 3228 0.8239 0.7527
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 929 3002 3228 0.9301 0.9018
Hs 578T Sigma A6730
0.12
uM
LJP5
 72
hr
 929 3129 3228 0.9695 0.9572
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 929 852 3228 0.2641 -0.0333
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 929 2782 3228 0.8619 0.8061
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 929 2372 3228 0.7350 0.6279
Hs 578T AZD-6482
0.12
uM
LJP5
 72
hr
 929 2916 3228 0.9035 0.8645
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 929 1262 3228 0.3911 0.1449
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 929 1326 3228 0.4110 0.1729
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 929 1482 3228 0.4591 0.2405
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 929 1883 3228 0.5833 0.4149
Hs 578T BI-2536
0.12
uM
LJP6
 72
hr
 929 946 3228 0.2932 0.0074
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 929 3259 3228 1.0097 1.0136
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 929 868 3228 0.2691 -0.0264
Hs 578T GDC-0980
0.12
uM
LJP5
 72
hr
 929 1782 3228 0.5522 0.3712
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 929 3327 3228 1.0309 1.0433
Hs 578T SB590885
0.12
uM
LJP5
 72
hr
 929 3796 3228 1.1760 1.2472
Hs 578T PIK-93
0.12
uM
LJP5
 72
hr
 929 3328 3228 1.0310 1.0435
Hs 578T KIN001-043
0.12
uM
LJP6
 72
hr
 929 3353 3228 1.0389 1.0546
Hs 578T Alpelisib
0.12
uM
LJP5
 72
hr
 929 2991 3228 0.9268 0.8972
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 929 1326 3228 0.4108 0.1726