LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1657 1848 5505 0.3357 0.0495
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1657 4547 5505 0.8259 0.7510
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1657 4811 5505 0.8740 0.8196
BT-20 XL147
3.33
uM
LJP5
 72
hr
 1657 4909 5505 0.8918 0.8451
BT-20 Saracatinib
3.33
uM
LJP6
 72
hr
 1657 3616 5505 0.6568 0.5090
BT-20 Selumetinib
3.33
uM
LJP6
 72
hr
 1657 5739 5505 1.0425 1.0608
BT-20 Sirolimus
3.33
uM
LJP6
 72
hr
 1657 3676 5505 0.6677 0.5245
BT-20 Sorafenib
3.33
uM
LJP6
 72
hr
 1657 4606 5505 0.8367 0.7663
BT-20 SU11274
3.33
uM
LJP5
 72
hr
 1657 4682 5505 0.8505 0.7860
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1657 3869 5505 0.7029 0.5748
BT-20 TGX221
3.33
uM
LJP5
 72
hr
 1657 5556 5505 1.0091 1.0131
BT-20 Torin1
3.33
uM
LJP6
 72
hr
 1657 1240 5505 0.2252 -0.1086
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1657 1050 5505 0.1908 -0.1578
BT-20 Tozasertib
3.33
uM
LJP5
 72
hr
 1657 1627 5505 0.2955 -0.0080
BT-20 Trametinib
3.33
uM
LJP5
 72
hr
 1657 4154 5505 0.7545 0.6487
BT-20 TWS119
3.33
uM
LJP5
 72
hr
 1657 4467 5505 0.8114 0.7301
BT-20 Vemurafenib
3.33
uM
LJP5
 72
hr
 1657 5138 5505 0.9332 0.9045
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1657 907 5505 0.1649 -0.1949
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1657 901 5505 0.1637 -0.1966
BT-20 WYE-125132
3.33
uM
LJP6
 72
hr
 1657 2216 5505 0.4025 0.1451
BT-20 WZ3105
3.33
uM
LJP5
 72
hr
 1657 1370 5505 0.2490 -0.0746
BT-20 XMD11-50
3.33
uM
LJP6
 72
hr
 1657 3453 5505 0.6272 0.4666
BT-20 Y39983
3.33
uM
LJP6
 72
hr
 1657 4304 5505 0.7818 0.6878
BT-20 YM 201636
3.33
uM
LJP5
 72
hr
 1657 3958 5505 0.7189 0.5978
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1657 1697 5505 0.3083 0.0103