LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1389 | 5505 | 0.2524 | -0.0697 |
BT-20 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1288 | 5505 | 0.2341 | -0.0959 |
BT-20 | MK2206 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2935 | 5505 | 0.5331 | 0.3319 |
BT-20 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3315 | 5505 | 0.6022 | 0.4308 |
BT-20 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5576 | 5505 | 1.0129 | 1.0185 |
BT-20 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4432 | 5505 | 0.8050 | 0.7210 |
BT-20 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5366 | 5505 | 0.9747 | 0.9638 |
BT-20 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1806 | 5505 | 0.3282 | 0.0387 |
BT-20 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2649 | 5505 | 0.4812 | 0.2577 |
BT-20 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2405 | 5505 | 0.4369 | 0.1943 |
BT-20 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4039 | 5505 | 0.7337 | 0.6190 |
BT-20 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 3503 | 5505 | 0.6363 | 0.4796 |
BT-20 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 6371 | 5505 | 1.1572 | 1.2249 |
BT-20 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5398 | 5505 | 0.9806 | 0.9722 |
BT-20 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4353 | 5505 | 0.7908 | 0.7006 |
BT-20 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1940 | 5505 | 0.3524 | 0.0734 |
BT-20 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4574 | 5505 | 0.8308 | 0.7579 |
BT-20 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1962 | 5505 | 0.3565 | 0.0792 |
BT-20 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5638 | 5505 | 1.0240 | 1.0344 |
BT-20 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1654 | 5505 | 0.3004 | -0.0010 |
BT-20 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1552 | 5505 | 0.2820 | -0.0273 |
BT-20 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4095 | 5505 | 0.7438 | 0.6334 |
BT-20 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2739 | 5505 | 0.4975 | 0.2810 |
BT-20 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1317 | 5505 | 0.2393 | -0.0885 |
BT-20 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1834 | 5505 | 0.3332 | 0.0460 |