LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1569 | 5505 | 0.2851 | -0.0229 |
BT-20 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2745 | 5505 | 0.4987 | 0.2827 |
BT-20 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1169 | 5505 | 0.2124 | -0.1269 |
BT-20 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 922 | 5505 | 0.1675 | -0.1912 |
BT-20 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1023 | 5505 | 0.1859 | -0.1648 |
BT-20 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1556 | 5505 | 0.2827 | -0.0263 |
BT-20 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 836 | 5505 | 0.1519 | -0.2135 |
BT-20 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1508 | 5505 | 0.2740 | -0.0388 |
BT-20 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 4562 | 5505 | 0.8287 | 0.7549 |
BT-20 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1851 | 5505 | 0.3362 | 0.0502 |
BT-20 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1646 | 5505 | 0.2991 | -0.0029 |
BT-20 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1686 | 5505 | 0.3064 | 0.0075 |
BT-20 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1155 | 5505 | 0.2098 | -0.1307 |
BT-20 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1222 | 5505 | 0.2221 | -0.1131 |
BT-20 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 5335 | 5505 | 0.9690 | 0.9557 |
BT-20 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 5018 | 5505 | 0.9114 | 0.8733 |
BT-20 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2006 | 5505 | 0.3644 | 0.0906 |
BT-20 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 3221 | 5505 | 0.5851 | 0.4064 |
BT-20 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1445 | 5505 | 0.2625 | -0.0552 |
BT-20 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1806 | 5505 | 0.3281 | 0.0386 |
BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 652 | 5505 | 0.1185 | -0.2613 |
BT-20 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2255 | 5505 | 0.4096 | 0.1553 |
BT-20 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1657 | 4287 | 5505 | 0.7787 | 0.6833 |
BT-20 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 904 | 5505 | 0.1642 | -0.1959 |
BT-20 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1145 | 5505 | 0.2080 | -0.1332 |