LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Selumetinib
0.37
uM
LJP6
 72
hr
 1657 5683 5505 1.0323 1.0463
BT-20 Sirolimus
0.37
uM
LJP6
 72
hr
 1657 3629 5505 0.6591 0.5123
BT-20 Sorafenib
0.37
uM
LJP6
 72
hr
 1657 4847 5505 0.8804 0.8288
BT-20 SU11274
0.37
uM
LJP5
 72
hr
 1657 5441 5505 0.9883 0.9832
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1657 5280 5505 0.9590 0.9414
BT-20 TGX221
0.37
uM
LJP5
 72
hr
 1657 5559 5505 1.0097 1.0139
BT-20 Torin1
0.37
uM
LJP6
 72
hr
 1657 1781 5505 0.3236 0.0321
BT-20 Torin2
0.37
uM
LJP5
 72
hr
 1657 1551 5505 0.2818 -0.0276
BT-20 Tozasertib
0.37
uM
LJP5
 72
hr
 1657 1709 5505 0.3104 0.0133
BT-20 Trametinib
0.37
uM
LJP5
 72
hr
 1657 4368 5505 0.7934 0.7043
BT-20 TWS119
0.37
uM
LJP5
 72
hr
 1657 5466 5505 0.9929 0.9899
BT-20 Vemurafenib
0.37
uM
LJP5
 72
hr
 1657 5543 5505 1.0069 1.0099
BT-20 Withaferin A
0.37
uM
LJP5
 72
hr
 1657 4776 5505 0.8675 0.8104
BT-20 Withaferin A
0.37
uM
LJP6
 72
hr
 1657 4431 5505 0.8049 0.7209
BT-20 WYE-125132
0.37
uM
LJP6
 72
hr
 1657 2430 5505 0.4415 0.2009
BT-20 WZ3105
0.37
uM
LJP5
 72
hr
 1657 1863 5505 0.3385 0.0535
BT-20 XMD11-50
0.37
uM
LJP6
 72
hr
 1657 4487 5505 0.8150 0.7353
BT-20 Y39983
0.37
uM
LJP6
 72
hr
 1657 4915 5505 0.8928 0.8467
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1657 5135 5505 0.9327 0.9037
BT-20 ZSTK474
0.37
uM
LJP6
 72
hr
 1657 3379 5505 0.6139 0.4475
BT-20 Afatinib
1.11
uM
LJP6
 72
hr
 1657 5087 5505 0.9241 0.8914
BT-20 Sigma A6730
1.11
uM
LJP5
 72
hr
 1657 4941 5505 0.8974 0.8533
BT-20 Alvocidib
1.11
uM
LJP6
 72
hr
 1657 1130 5505 0.2053 -0.1371
BT-20 AT-7519
1.11
uM
LJP6
 72
hr
 1657 1474 5505 0.2677 -0.0478
BT-20 AZD 5438
1.11
uM
LJP6
 72
hr
 1657 1829 5505 0.3323 0.0447