LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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Hs 578T | A443654 | 0.12 | uM | LJP6 | 72 | hr | 929 | 1547 | 3228 | 0.4794 | 0.2690 |
Hs 578T | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 929 | 3055 | 3228 | 0.9466 | 0.9250 |
Hs 578T | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 929 | 3107 | 3228 | 0.9626 | 0.9475 |
Hs 578T | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 929 | 3479 | 3228 | 1.0779 | 1.1094 |
Hs 578T | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 929 | 2335 | 3228 | 0.7235 | 0.6117 |
Hs 578T | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 929 | 2364 | 3228 | 0.7323 | 0.6241 |
Hs 578T | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 929 | 1375 | 3228 | 0.4260 | 0.1939 |
Hs 578T | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 929 | 3076 | 3228 | 0.9531 | 0.9341 |
Hs 578T | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 929 | 2881 | 3228 | 0.8927 | 0.8493 |
Hs 578T | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3047 | 3228 | 0.9441 | 0.9215 |
Hs 578T | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 929 | 3153 | 3228 | 0.9770 | 0.9676 |
Hs 578T | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 929 | 3435 | 3228 | 1.0643 | 1.0903 |
Hs 578T | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 929 | 1323 | 3228 | 0.4100 | 0.1714 |
Hs 578T | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 929 | 808 | 3228 | 0.2505 | -0.0525 |
Hs 578T | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 929 | 3128 | 3228 | 0.9691 | 0.9566 |
Hs 578T | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3218 | 3228 | 0.9970 | 0.9958 |
Hs 578T | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3415 | 3228 | 1.0581 | 1.0816 |
Hs 578T | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 3214 | 3228 | 0.9956 | 0.9939 |
Hs 578T | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 2752 | 3228 | 0.8526 | 0.7931 |
Hs 578T | Dasatinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 1756 | 3228 | 0.5441 | 0.3598 |
Hs 578T | Dasatinib | 0.12 | uM | LJP6 | 72 | hr | 929 | 1205 | 3228 | 0.3733 | 0.1200 |
Hs 578T | Dovitinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 2026 | 3228 | 0.6278 | 0.4774 |
Hs 578T | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 929 | 3263 | 3228 | 1.0110 | 1.0155 |
Hs 578T | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 3071 | 3228 | 0.9516 | 0.9320 |
Hs 578T | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 929 | 2832 | 3228 | 0.8773 | 0.8277 |