LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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Hs 578T | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 929 | 1201 | 3228 | 0.3723 | 0.1185 |
Hs 578T | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 929 | 1655 | 3228 | 0.5129 | 0.3160 |
Hs 578T | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 929 | 3280 | 3228 | 1.0162 | 1.0227 |
Hs 578T | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 929 | 3059 | 3228 | 0.9478 | 0.9268 |
Hs 578T | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 929 | 1682 | 3228 | 0.5211 | 0.3275 |
Hs 578T | R406 | 1.11 | uM | LJP6 | 72 | hr | 929 | 2614 | 3228 | 0.8100 | 0.7332 |
Hs 578T | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 929 | 1720 | 3228 | 0.5329 | 0.3441 |
Hs 578T | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 929 | 3132 | 3228 | 0.9702 | 0.9582 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 929 | 1275 | 3228 | 0.3952 | 0.1507 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 929 | 1326 | 3228 | 0.4109 | 0.1727 |
Hs 578T | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 929 | 1568 | 3228 | 0.4858 | 0.2780 |
Hs 578T | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 929 | 1629 | 3228 | 0.5047 | 0.3045 |
Hs 578T | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 929 | 2990 | 3228 | 0.9263 | 0.8964 |
Hs 578T | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 929 | 1005 | 3228 | 0.3114 | 0.0331 |
Hs 578T | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 929 | 2291 | 3228 | 0.7099 | 0.5927 |
Hs 578T | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 929 | 796 | 3228 | 0.2468 | -0.0577 |
Hs 578T | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 929 | 2102 | 3228 | 0.6512 | 0.5102 |
Hs 578T | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 929 | 2823 | 3228 | 0.8745 | 0.8238 |
Hs 578T | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 929 | 3363 | 3228 | 1.0419 | 1.0588 |
Hs 578T | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 929 | 2328 | 3228 | 0.7213 | 0.6086 |
Hs 578T | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 929 | 2187 | 3228 | 0.6775 | 0.5471 |
Hs 578T | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 929 | 3124 | 3228 | 0.9680 | 0.9550 |
Hs 578T | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 929 | 3019 | 3228 | 0.9352 | 0.9091 |
Hs 578T | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 929 | 3133 | 3228 | 0.9708 | 0.9589 |
Hs 578T | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 929 | 3128 | 3228 | 0.9691 | 0.9566 |