LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
10.0
uM
LJP6
 72
hr
 929 864 3228 0.2678 -0.0282
Hs 578T Lapatinib
10.0
uM
LJP6
 72
hr
 929 2495 3228 0.7731 0.6814
Hs 578T LDN-193189
10.0
uM
LJP5
 72
hr
 929 515 3228 0.1597 -0.1799
Hs 578T Linifanib
10.0
uM
LJP6
 72
hr
 929 2426 3228 0.7516 0.6512
Hs 578T Linsitinib
10.0
uM
LJP5
 72
hr
 929 2646 3228 0.8197 0.7468
Hs 578T Mitoxantrone
10.0
uM
LJP5
 72
hr
 929 442 3228 0.1369 -0.2120
Hs 578T Mitoxantrone
10.0
uM
LJP6
 72
hr
 929 466 3228 0.1446 -0.2012
Hs 578T MK2206
10.0
uM
LJP6
 72
hr
 929 1876 3228 0.5813 0.4120
Hs 578T Neratinib
10.0
uM
LJP5
 72
hr
 929 933 3228 0.2891 0.0018
Hs 578T Nilotinib
10.0
uM
LJP5
 72
hr
 929 1149 3228 0.3560 0.0957
Hs 578T Nintedanib
10.0
uM
LJP6
 72
hr
 929 999 3228 0.3095 0.0303
Hs 578T NU7441
10.0
uM
LJP5
 72
hr
 929 1186 3228 0.3674 0.1117
Hs 578T Dactolisib
10.0
uM
LJP5
 72
hr
 929 1181 3228 0.3661 0.1098
Hs 578T NVP-TAE684
10.0
uM
LJP6
 72
hr
 929 815 3228 0.2525 -0.0497
Hs 578T Palbociclib
10.0
uM
LJP6
 72
hr
 929 1563 3228 0.4844 0.2760
Hs 578T PD0325901
10.0
uM
LJP5
 72
hr
 929 1327 3228 0.4113 0.1733
Hs 578T PD0325901
10.0
uM
LJP6
 72
hr
 929 1174 3228 0.3637 0.1065
Hs 578T PD173074
10.0
uM
LJP6
 72
hr
 929 1530 3228 0.4740 0.2613
Hs 578T PD184352
10.0
uM
LJP5
 72
hr
 929 1578 3228 0.4890 0.2825
Hs 578T Pelitinib
10.0
uM
LJP5
 72
hr
 929 718 3228 0.2226 -0.0916
Hs 578T PF431396
10.0
uM
LJP5
 72
hr
 929 873 3228 0.2704 -0.0245
Hs 578T PF477736
10.0
uM
LJP5
 72
hr
 929 1036 3228 0.3209 0.0464
Hs 578T PF562271
10.0
uM
LJP6
 72
hr
 929 918 3228 0.2845 -0.0047
Hs 578T PHA-665752
10.0
uM
LJP5
 72
hr
 929 1974 3228 0.6115 0.4545
Hs 578T PHA-793887
10.0
uM
LJP6
 72
hr
 929 836 3228 0.2590 -0.0406