LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 929 774 3228 0.2400 -0.0672
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 929 775 3228 0.2401 -0.0671
Hs 578T MK2206
1.11
uM
LJP6
 72
hr
 929 2175 3228 0.6739 0.5421
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 929 1952 3228 0.6049 0.4452
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 929 3608 3228 1.1179 1.1656
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 929 1755 3228 0.5437 0.3592
Hs 578T NU7441
1.11
uM
LJP5
 72
hr
 929 2580 3228 0.7992 0.7181
Hs 578T Dactolisib
1.11
uM
LJP5
 72
hr
 929 1360 3228 0.4215 0.1877
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 929 1773 3228 0.5495 0.3673
Hs 578T Palbociclib
1.11
uM
LJP6
 72
hr
 929 1645 3228 0.5097 0.3115
Hs 578T PD0325901
1.11
uM
LJP5
 72
hr
 929 1593 3228 0.4936 0.2889
Hs 578T PD0325901
1.11
uM
LJP6
 72
hr
 929 1477 3228 0.4577 0.2384
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 929 2904 3228 0.8998 0.8593
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 929 1843 3228 0.5709 0.3975
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 929 2716 3228 0.8415 0.7774
Hs 578T PF431396
1.11
uM
LJP5
 72
hr
 929 1588 3228 0.4921 0.2869
Hs 578T PF477736
1.11
uM
LJP5
 72
hr
 929 1210 3228 0.3748 0.1221
Hs 578T PF562271
1.11
uM
LJP6
 72
hr
 929 2142 3228 0.6638 0.5279
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 929 3174 3228 0.9834 0.9766
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 929 1246 3228 0.3862 0.1381
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 929 1298 3228 0.4022 0.1606
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 929 3783 3228 1.1719 1.2414
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 929 1970 3228 0.6104 0.4529
Hs 578T QL-XII-47
1.11
uM
LJP6
 72
hr
 929 1965 3228 0.6089 0.4509
Hs 578T Radicicol
1.11
uM
LJP5
 72
hr
 929 2055 3228 0.6366 0.4897