LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T R406
0.12
uM
LJP6
 72
hr
 929 2945 3228 0.9124 0.8770
Hs 578T Pictilisib
0.12
uM
LJP6
 72
hr
 929 2257 3228 0.6993 0.5777
Hs 578T Gefitinib
0.12
uM
LJP6
 72
hr
 929 3182 3228 0.9857 0.9800
Hs 578T Geldanamycin
0.12
uM
LJP5
 72
hr
 929 1445 3228 0.4478 0.2247
Hs 578T Geldanamycin
0.12
uM
LJP6
 72
hr
 929 1412 3228 0.4374 0.2100
Hs 578T GSK1059615
0.12
uM
LJP5
 72
hr
 929 2877 3228 0.8915 0.8476
Hs 578T GSK1059615
0.12
uM
LJP6
 72
hr
 929 2554 3228 0.7912 0.7068
Hs 578T GSK1904529A
0.12
uM
LJP6
 72
hr
 929 3131 3228 0.9701 0.9581
Hs 578T Omipalisib
0.12
uM
LJP6
 72
hr
 929 1291 3228 0.4001 0.1577
Hs 578T GSK 690693
0.12
uM
LJP5
 72
hr
 929 2504 3228 0.7757 0.6850
Hs 578T GW843682X
0.12
uM
LJP6
 72
hr
 929 2312 3228 0.7164 0.6018
Hs 578T HG-5-113-01
0.12
uM
LJP5
 72
hr
 929 2910 3228 0.9015 0.8616
Hs 578T HG-5-88-01
0.12
uM
LJP6
 72
hr
 929 3045 3228 0.9433 0.9204
Hs 578T Imatinib
0.12
uM
LJP6
 72
hr
 929 3189 3228 0.9880 0.9832
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 929 3394 3228 1.0514 1.0722
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 929 2955 3228 0.9154 0.8812
Hs 578T Lapatinib
0.12
uM
LJP6
 72
hr
 929 3124 3228 0.9679 0.9549
Hs 578T LDN-193189
0.12
uM
LJP5
 72
hr
 929 3017 3228 0.9346 0.9082
Hs 578T Linifanib
0.12
uM
LJP6
 72
hr
 929 3121 3228 0.9669 0.9536
Hs 578T Linsitinib
0.12
uM
LJP5
 72
hr
 929 3137 3228 0.9718 0.9604
Hs 578T Mitoxantrone
0.12
uM
LJP5
 72
hr
 929 1017 3228 0.3151 0.0382
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 929 941 3228 0.2916 0.0053
Hs 578T MK2206
0.12
uM
LJP6
 72
hr
 929 2641 3228 0.8183 0.7449
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 929 2706 3228 0.8385 0.7732
Hs 578T Nilotinib
0.12
uM
LJP5
 72
hr
 929 3674 3228 1.1381 1.1940