LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Radicicol
1.11
uM
LJP6
 72
hr
 929 1784 3228 0.5527 0.3718
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 929 3131 3228 0.9700 0.9579
Hs 578T Ruxolitinib
1.11
uM
LJP5
 72
hr
 929 3092 3228 0.9580 0.9410
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 929 3216 3228 0.9964 0.9949
Hs 578T Saracatinib
1.11
uM
LJP6
 72
hr
 929 2202 3228 0.6824 0.5540
Hs 578T Selumetinib
1.11
uM
LJP6
 72
hr
 929 1707 3228 0.5288 0.3383
Hs 578T Sirolimus
1.11
uM
LJP6
 72
hr
 929 2298 3228 0.7120 0.5956
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 929 4060 3228 1.2579 1.3622
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 929 2843 3228 0.8809 0.8328
Hs 578T Fedratinib
1.11
uM
LJP5
 72
hr
 929 2462 3228 0.7628 0.6669
Hs 578T TGX221
1.11
uM
LJP5
 72
hr
 929 2949 3228 0.9136 0.8786
Hs 578T Torin1
1.11
uM
LJP6
 72
hr
 929 1237 3228 0.3834 0.1342
Hs 578T Torin2
1.11
uM
LJP5
 72
hr
 929 1089 3228 0.3375 0.0696
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 929 1283 3228 0.3975 0.1539
Hs 578T Trametinib
1.11
uM
LJP5
 72
hr
 929 1464 3228 0.4537 0.2329
Hs 578T TWS119
1.11
uM
LJP5
 72
hr
 929 2872 3228 0.8897 0.8451
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 929 3362 3228 1.0417 1.0586
Hs 578T Withaferin A
1.11
uM
LJP5
 72
hr
 929 840 3228 0.2603 -0.0387
Hs 578T Withaferin A
1.11
uM
LJP6
 72
hr
 929 738 3228 0.2287 -0.0830
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 929 1280 3228 0.3967 0.1529
Hs 578T WZ3105
1.11
uM
LJP5
 72
hr
 929 855 3228 0.2650 -0.0322
Hs 578T XMD11-50
1.11
uM
LJP6
 72
hr
 929 2327 3228 0.7210 0.6082
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 929 2493 3228 0.7723 0.6802
Hs 578T YM 201636
1.11
uM
LJP5
 72
hr
 929 2926 3228 0.9065 0.8688
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 929 1575 3228 0.4880 0.2811