LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 929 2740 3228 0.8488 0.7877
Hs 578T Sigma A6730
3.33
uM
LJP5
 72
hr
 929 2933 3228 0.9087 0.8718
Hs 578T Alvocidib
3.33
uM
LJP6
 72
hr
 929 751 3228 0.2327 -0.0775
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 929 737 3228 0.2283 -0.0836
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 929 941 3228 0.2916 0.0053
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 929 2267 3228 0.7024 0.5821
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 929 853 3228 0.2644 -0.0330
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 929 1264 3228 0.3916 0.1456
Hs 578T AZD8330
3.33
uM
LJP5
 72
hr
 929 1544 3228 0.4783 0.2674
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 929 1684 3228 0.5219 0.3286
Hs 578T BI-2536
3.33
uM
LJP6
 72
hr
 929 977 3228 0.3028 0.0209
Hs 578T BMS345541
3.33
uM
LJP6
 72
hr
 929 2612 3228 0.8093 0.7322
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 929 795 3228 0.2464 -0.0583
Hs 578T GDC-0980
3.33
uM
LJP5
 72
hr
 929 1311 3228 0.4063 0.1664
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 929 3287 3228 1.0183 1.0256
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 929 3939 3228 1.2202 1.3093
Hs 578T PIK-93
3.33
uM
LJP5
 72
hr
 929 2309 3228 0.7155 0.6005
Hs 578T KIN001-043
3.33
uM
LJP6
 72
hr
 929 3092 3228 0.9581 0.9411
Hs 578T Alpelisib
3.33
uM
LJP5
 72
hr
 929 2563 3228 0.7942 0.7110
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 929 1350 3228 0.4183 0.1832
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 929 638 3228 0.1976 -0.1267
Hs 578T OSI-027
3.33
uM
LJP6
 72
hr
 929 1500 3228 0.4649 0.2486
Hs 578T XMD11-85h
3.33
uM
LJP6
 72
hr
 929 2808 3228 0.8699 0.8173
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 929 1438 3228 0.4457 0.2216
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 929 1092 3228 0.3385 0.0711