LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Selumetinib
0.12
uM
LJP6
 72
hr
 929 1796 3228 0.5564 0.3770
Hs 578T Sirolimus
0.12
uM
LJP6
 72
hr
 929 2222 3228 0.6884 0.5625
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 929 3812 3228 1.1810 1.2542
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 929 3198 3228 0.9907 0.9869
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 929 3223 3228 0.9986 0.9981
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 929 2824 3228 0.8750 0.8245
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 929 1391 3228 0.4310 0.2010
Hs 578T Torin2
0.12
uM
LJP5
 72
hr
 929 1290 3228 0.3998 0.1572
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 929 1299 3228 0.4026 0.1611
Hs 578T Trametinib
0.12
uM
LJP5
 72
hr
 929 1458 3228 0.4519 0.2303
Hs 578T TWS119
0.12
uM
LJP5
 72
hr
 929 3201 3228 0.9918 0.9885
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 929 3356 3228 1.0396 1.0557
Hs 578T Withaferin A
0.12
uM
LJP5
 72
hr
 929 3298 3228 1.0219 1.0307
Hs 578T Withaferin A
0.12
uM
LJP6
 72
hr
 929 3273 3228 1.0140 1.0197
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 929 1340 3228 0.4151 0.1787
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 929 835 3228 0.2589 -0.0407
Hs 578T XMD11-50
0.12
uM
LJP6
 72
hr
 929 3059 3228 0.9478 0.9268
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 929 2577 3228 0.7985 0.7171
Hs 578T YM 201636
0.12
uM
LJP5
 72
hr
 929 3228 3228 1.0001 1.0001
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 929 2261 3228 0.7006 0.5796
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 929 3030 3228 0.9389 0.9141
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 929 3035 3228 0.9402 0.9160
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 929 734 3228 0.2274 -0.0849
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 929 967 3228 0.2997 0.0166
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 929 1482 3228 0.4593 0.2407