LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 PD0325901
10.0
uM
LJP5
72
hr
1657 3192 5505 0.5798 0.3988
BT-20 PD0325901
10.0
uM
LJP6
72
hr
1657 3157 5505 0.5734 0.3896
BT-20 PD173074
10.0
uM
LJP6
72
hr
1657 5503 5505 0.9996 0.9994
BT-20 PD184352
10.0
uM
LJP5
72
hr
1657 2987 5505 0.5426 0.3455
BT-20 Pelitinib
10.0
uM
LJP5
72
hr
1657 1202 5505 0.2184 -0.1183
BT-20 PF431396
10.0
uM
LJP5
72
hr
1657 1706 5505 0.3099 0.0125
BT-20 PF477736
10.0
uM
LJP5
72
hr
1657 2114 5505 0.3840 0.1186
BT-20 PF562271
10.0
uM
LJP6
72
hr
1657 1301 5505 0.2364 -0.0925
BT-20 PHA-665752
10.0
uM
LJP5
72
hr
1657 4059 5505 0.7372 0.6240
BT-20 PHA-793887
10.0
uM
LJP6
72
hr
1657 1369 5505 0.2488 -0.0749
BT-20 PI103
10.0
uM
LJP6
72
hr
1657 1434 5505 0.2605 -0.0581
BT-20 PLX-4720
10.0
uM
LJP5
72
hr
1657 2924 5505 0.5311 0.3291
BT-20 QL-X-138
10.0
uM
LJP6
72
hr
1657 1231 5505 0.2237 -0.1108
BT-20 QL-XII-47
10.0
uM
LJP6
72
hr
1657 799 5505 0.1452 -0.2231
BT-20 Radicicol
10.0
uM
LJP5
72
hr
1657 1506 5505 0.2737 -0.0393
BT-20 Radicicol
10.0
uM
LJP6
72
hr
1657 1525 5505 0.2770 -0.0345
BT-20 Seliciclib
10.0
uM
LJP5
72
hr
1657 2184 5505 0.3967 0.1369
BT-20 Ruxolitinib
10.0
uM
LJP5
72
hr
1657 3984 5505 0.7237 0.6047
BT-20 XL147
10.0
uM
LJP5
72
hr
1657 2185 5505 0.3969 0.1370
BT-20 Saracatinib
10.0
uM
LJP6
72
hr
1657 2213 5505 0.4020 0.1443
BT-20 Selumetinib
10.0
uM
LJP6
72
hr
1657 5417 5505 0.9840 0.9770
BT-20 Sirolimus
10.0
uM
LJP6
72
hr
1657 3799 5505 0.6900 0.5565
BT-20 Sorafenib
10.0
uM
LJP6
72
hr
1657 2825 5505 0.5132 0.3034
BT-20 SU11274
10.0
uM
LJP5
72
hr
1657 2093 5505 0.3803 0.1133
BT-20 Fedratinib
10.0
uM
LJP5
72
hr
1657 1702 5505 0.3091 0.0115