LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1417 | 5505 | 0.2574 | -0.0626 |
| BT-20 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 3826 | 5505 | 0.6950 | 0.5636 |
| BT-20 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4985 | 5505 | 0.9055 | 0.8648 |
| BT-20 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5631 | 5505 | 1.0228 | 1.0326 |
| BT-20 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1866 | 5505 | 0.3390 | 0.0542 |
| BT-20 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4510 | 5505 | 0.8193 | 0.7414 |
| BT-20 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5117 | 5505 | 0.9295 | 0.8991 |
| BT-20 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4768 | 5505 | 0.8661 | 0.8084 |
| BT-20 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5860 | 5505 | 1.0645 | 1.0923 |
| BT-20 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4955 | 5505 | 0.9001 | 0.8571 |
| BT-20 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1657 | 1493 | 5505 | 0.2713 | -0.0426 |
| BT-20 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1471 | 5505 | 0.2672 | -0.0485 |
| BT-20 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 3538 | 5505 | 0.6427 | 0.4888 |
| BT-20 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 3794 | 5505 | 0.6892 | 0.5553 |
| BT-20 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5335 | 5505 | 0.9691 | 0.9557 |
| BT-20 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4810 | 5505 | 0.8737 | 0.8192 |
| BT-20 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5599 | 5505 | 1.0170 | 1.0243 |
| BT-20 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 1960 | 5505 | 0.3561 | 0.0786 |
| BT-20 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4275 | 5505 | 0.7765 | 0.6803 |
| BT-20 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 2553 | 5505 | 0.4638 | 0.2328 |
| BT-20 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4787 | 5505 | 0.8695 | 0.8132 |
| BT-20 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4352 | 5505 | 0.7905 | 0.7002 |
| BT-20 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 6376 | 5505 | 1.1581 | 1.2263 |
| BT-20 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5512 | 5505 | 1.0013 | 1.0018 |
| BT-20 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4369 | 5505 | 0.7936 | 0.7046 |