LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 772 | 5505 | 0.1403 | -0.2300 |
BT-20 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 837 | 5505 | 0.1520 | -0.2133 |
BT-20 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1657 | 5435 | 5505 | 0.9872 | 0.9816 |
BT-20 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1130 | 5505 | 0.2053 | -0.1371 |
BT-20 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 3072 | 5505 | 0.5581 | 0.3677 |
BT-20 | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1730 | 5505 | 0.3142 | 0.0188 |
BT-20 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1376 | 5505 | 0.2500 | -0.0731 |
BT-20 | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 3006 | 5505 | 0.5461 | 0.3506 |
BT-20 | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 5268 | 5505 | 0.9570 | 0.9384 |
BT-20 | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1246 | 5505 | 0.2264 | -0.1068 |
BT-20 | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1813 | 5505 | 0.3294 | 0.0405 |
BT-20 | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 4252 | 5505 | 0.7724 | 0.6744 |
BT-20 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 545 | 5505 | 0.0991 | -0.2890 |
BT-20 | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2877 | 5505 | 0.5227 | 0.3170 |
BT-20 | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 4391 | 5505 | 0.7976 | 0.7104 |
BT-20 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1047 | 5505 | 0.1902 | -0.1587 |
BT-20 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1657 | 924 | 5505 | 0.1679 | -0.1906 |
BT-20 | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1838 | 5505 | 0.3340 | 0.0470 |
BT-20 | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2883 | 5505 | 0.5238 | 0.3186 |
BT-20 | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2060 | 5505 | 0.3742 | 0.1045 |
BT-20 | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 3332 | 5505 | 0.6053 | 0.4352 |
BT-20 | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2467 | 5505 | 0.4481 | 0.2103 |
BT-20 | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1976 | 5505 | 0.3590 | 0.0829 |
BT-20 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1604 | 5505 | 0.2915 | -0.0138 |
BT-20 | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2337 | 5505 | 0.4246 | 0.1767 |