LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | TGX221 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 5980 | 5505 | 1.0862 | 1.1234 |
BT-20 | Torin1 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1080 | 5505 | 0.1962 | -0.1501 |
BT-20 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1242 | 5505 | 0.2257 | -0.1080 |
BT-20 | Tozasertib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1660 | 5505 | 0.3016 | 0.0007 |
BT-20 | Trametinib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 4343 | 5505 | 0.7888 | 0.6979 |
BT-20 | TWS119 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1933 | 5505 | 0.3512 | 0.0716 |
BT-20 | Vemurafenib | 10.0 | uM | LJP5 | 72 | hr | 1657 | 3848 | 5505 | 0.6989 | 0.5692 |
BT-20 | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 1657 | 933 | 5505 | 0.1695 | -0.1883 |
BT-20 | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 1657 | 931 | 5505 | 0.1692 | -0.1887 |
BT-20 | WYE-125132 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2019 | 5505 | 0.3668 | 0.0940 |
BT-20 | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 1126 | 5505 | 0.2046 | -0.1380 |
BT-20 | XMD11-50 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2366 | 5505 | 0.4299 | 0.1842 |
BT-20 | Y39983 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 2245 | 5505 | 0.4079 | 0.1528 |
BT-20 | YM 201636 | 10.0 | uM | LJP5 | 72 | hr | 1657 | 2142 | 5505 | 0.3892 | 0.1260 |
BT-20 | ZSTK474 | 10.0 | uM | LJP6 | 72 | hr | 1657 | 1543 | 5505 | 0.2803 | -0.0297 |
Hs 578T | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 929 | 3069 | 3228 | 0.9509 | 0.9311 |
Hs 578T | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3170 | 3228 | 0.9822 | 0.9750 |
Hs 578T | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 929 | 2245 | 3228 | 0.6956 | 0.5725 |
Hs 578T | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 929 | 3200 | 3228 | 0.9913 | 0.9878 |
Hs 578T | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 929 | 2947 | 3228 | 0.9129 | 0.8777 |
Hs 578T | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3064 | 3228 | 0.9492 | 0.9286 |
Hs 578T | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 929 | 1764 | 3228 | 0.5466 | 0.3633 |
Hs 578T | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 929 | 1457 | 3228 | 0.4516 | 0.2299 |
Hs 578T | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 929 | 1531 | 3228 | 0.4745 | 0.2621 |
Hs 578T | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 929 | 1898 | 3228 | 0.5880 | 0.4214 |