LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TGX221
10.0
uM
LJP5
72
hr
1657 5980 5505 1.0862 1.1234
BT-20 Torin1
10.0
uM
LJP6
72
hr
1657 1080 5505 0.1962 -0.1501
BT-20 Torin2
10.0
uM
LJP5
72
hr
1657 1242 5505 0.2257 -0.1080
BT-20 Tozasertib
10.0
uM
LJP5
72
hr
1657 1660 5505 0.3016 0.0007
BT-20 Trametinib
10.0
uM
LJP5
72
hr
1657 4343 5505 0.7888 0.6979
BT-20 TWS119
10.0
uM
LJP5
72
hr
1657 1933 5505 0.3512 0.0716
BT-20 Vemurafenib
10.0
uM
LJP5
72
hr
1657 3848 5505 0.6989 0.5692
BT-20 Withaferin A
10.0
uM
LJP5
72
hr
1657 933 5505 0.1695 -0.1883
BT-20 Withaferin A
10.0
uM
LJP6
72
hr
1657 931 5505 0.1692 -0.1887
BT-20 WYE-125132
10.0
uM
LJP6
72
hr
1657 2019 5505 0.3668 0.0940
BT-20 WZ3105
10.0
uM
LJP5
72
hr
1657 1126 5505 0.2046 -0.1380
BT-20 XMD11-50
10.0
uM
LJP6
72
hr
1657 2366 5505 0.4299 0.1842
BT-20 Y39983
10.0
uM
LJP6
72
hr
1657 2245 5505 0.4079 0.1528
BT-20 YM 201636
10.0
uM
LJP5
72
hr
1657 2142 5505 0.3892 0.1260
BT-20 ZSTK474
10.0
uM
LJP6
72
hr
1657 1543 5505 0.2803 -0.0297
Hs 578T Afatinib
0.04
uM
LJP6
72
hr
929 3069 3228 0.9509 0.9311
Hs 578T Sigma A6730
0.04
uM
LJP5
72
hr
929 3170 3228 0.9822 0.9750
Hs 578T Alvocidib
0.04
uM
LJP6
72
hr
929 2245 3228 0.6956 0.5725
Hs 578T AT-7519
0.04
uM
LJP6
72
hr
929 3200 3228 0.9913 0.9878
Hs 578T AZD 5438
0.04
uM
LJP6
72
hr
929 2947 3228 0.9129 0.8777
Hs 578T AZD-6482
0.04
uM
LJP5
72
hr
929 3064 3228 0.9492 0.9286
Hs 578T AZD7762
0.04
uM
LJP6
72
hr
929 1764 3228 0.5466 0.3633
Hs 578T AZD8055
0.04
uM
LJP6
72
hr
929 1457 3228 0.4516 0.2299
Hs 578T AZD8330
0.04
uM
LJP5
72
hr
929 1531 3228 0.4745 0.2621
Hs 578T Barasertib
0.04
uM
LJP5
72
hr
929 1898 3228 0.5880 0.4214