LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1374 | 3228 | 0.4256 | 0.1935 |
Hs 578T | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1254 | 3228 | 0.3885 | 0.1413 |
Hs 578T | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 929 | 2877 | 3228 | 0.8913 | 0.8473 |
Hs 578T | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1748 | 3228 | 0.5415 | 0.3562 |
Hs 578T | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 929 | 2891 | 3228 | 0.8957 | 0.8535 |
Hs 578T | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1369 | 3228 | 0.4241 | 0.1913 |
Hs 578T | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1120 | 3228 | 0.3472 | 0.0833 |
Hs 578T | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1906 | 3228 | 0.5906 | 0.4250 |
Hs 578T | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 929 | 3151 | 3228 | 0.9763 | 0.9668 |
Hs 578T | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1057 | 3228 | 0.3277 | 0.0559 |
Hs 578T | PI103 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1285 | 3228 | 0.3981 | 0.1548 |
Hs 578T | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 929 | 3603 | 3228 | 1.1164 | 1.1634 |
Hs 578T | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1786 | 3228 | 0.5534 | 0.3728 |
Hs 578T | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1321 | 3228 | 0.4094 | 0.1707 |
Hs 578T | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 929 | 1252 | 3228 | 0.3880 | 0.1406 |
Hs 578T | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 929 | 1292 | 3228 | 0.4002 | 0.1578 |
Hs 578T | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 929 | 3177 | 3228 | 0.9843 | 0.9779 |
Hs 578T | Ruxolitinib | 3.33 | uM | LJP5 | 72 | hr | 929 | 2948 | 3228 | 0.9135 | 0.8785 |
Hs 578T | XL147 | 3.33 | uM | LJP5 | 72 | hr | 929 | 3025 | 3228 | 0.9371 | 0.9117 |
Hs 578T | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 929 | 1991 | 3228 | 0.6169 | 0.4620 |
Hs 578T | Selumetinib | 3.33 | uM | LJP6 | 72 | hr | 929 | 1651 | 3228 | 0.5115 | 0.3140 |
Hs 578T | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 929 | 2245 | 3228 | 0.6955 | 0.5724 |
Hs 578T | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 929 | 3894 | 3228 | 1.2063 | 1.2897 |
Hs 578T | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 929 | 2671 | 3228 | 0.8276 | 0.7580 |
Hs 578T | Fedratinib | 3.33 | uM | LJP5 | 72 | hr | 929 | 1581 | 3228 | 0.4899 | 0.2837 |