LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 513 3659 10401 0.3518 0.3181
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 513 9497 10401 0.9131 0.9086
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 513 11587 10401 1.1140 1.1199
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 513 10462 10401 1.0059 1.0062
MCF 10A Fedratinib
0.04
uM
LJP5
 72
hr
 513 10336 10401 0.9938 0.9935
MCF 10A TGX221
0.04
uM
LJP5
 72
hr
 513 8988 10401 0.8641 0.8571
MCF 10A Torin1
0.04
uM
LJP6
 72
hr
 513 2067 10401 0.1988 0.1572
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 513 818 10401 0.0787 0.0308
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 513 1653 10401 0.1590 0.1153
MCF 10A Trametinib
0.04
uM
LJP5
 72
hr
 513 675 10401 0.0649 0.0164
MCF 10A TWS119
0.04
uM
LJP5
 72
hr
 513 10892 10401 1.0472 1.0497
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 513 10043 10401 0.9656 0.9638
MCF 10A Withaferin A
0.04
uM
LJP5
 72
hr
 513 10161 10401 0.9770 0.9758
MCF 10A Withaferin A
0.04
uM
LJP6
 72
hr
 513 10502 10401 1.0098 1.0103
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 513 2567 10401 0.2468 0.2077
MCF 10A WZ3105
0.04
uM
LJP5
 72
hr
 513 2104 10401 0.2023 0.1609
MCF 10A XMD11-50
0.04
uM
LJP6
 72
hr
 513 9828 10401 0.9449 0.9421
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 513 9617 10401 0.9246 0.9207
MCF 10A YM 201636
0.04
uM
LJP5
 72
hr
 513 10774 10401 1.0358 1.0377
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 513 7992 10401 0.7684 0.7564
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 513 427 10401 0.0411 -0.0087
MCF 10A Sigma A6730
0.12
uM
LJP5
 72
hr
 513 9681 10401 0.9308 0.9272
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 513 486 10401 0.0468 -0.0027
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 513 7852 10401 0.7549 0.7422
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 513 5533 10401 0.5320 0.5077