LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T GSK1059615
3.33
uM
LJP5
 72
hr
 929 1057 3228 0.3277 0.0559
Hs 578T GSK1059615
3.33
uM
LJP6
 72
hr
 929 1302 3228 0.4035 0.1624
Hs 578T GSK1904529A
3.33
uM
LJP6
 72
hr
 929 3087 3228 0.9565 0.9389
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 929 940 3228 0.2914 0.0050
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 929 2298 3228 0.7119 0.5954
Hs 578T GW843682X
3.33
uM
LJP6
 72
hr
 929 847 3228 0.2624 -0.0358
Hs 578T HG-5-113-01
3.33
uM
LJP5
 72
hr
 929 1400 3228 0.4339 0.2051
Hs 578T HG-5-88-01
3.33
uM
LJP6
 72
hr
 929 2708 3228 0.8390 0.7739
Hs 578T Imatinib
3.33
uM
LJP6
 72
hr
 929 3546 3228 1.0987 1.1386
Hs 578T JNK-9L
3.33
uM
LJP6
 72
hr
 929 1294 3228 0.4011 0.1590
Hs 578T JW-7-24-1
3.33
uM
LJP6
 72
hr
 929 1750 3228 0.5421 0.3570
Hs 578T Lapatinib
3.33
uM
LJP6
 72
hr
 929 3262 3228 1.0105 1.0148
Hs 578T LDN-193189
3.33
uM
LJP5
 72
hr
 929 2511 3228 0.7781 0.6884
Hs 578T Linifanib
3.33
uM
LJP6
 72
hr
 929 3085 3228 0.9558 0.9379
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 929 3132 3228 0.9702 0.9582
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 929 530 3228 0.1643 -0.1735
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 929 550 3228 0.1706 -0.1647
Hs 578T MK2206
3.33
uM
LJP6
 72
hr
 929 2157 3228 0.6683 0.5342
Hs 578T Neratinib
3.33
uM
LJP5
 72
hr
 929 1619 3228 0.5018 0.3003
Hs 578T Nilotinib
3.33
uM
LJP5
 72
hr
 929 3664 3228 1.1353 1.1899
Hs 578T Nintedanib
3.33
uM
LJP6
 72
hr
 929 1395 3228 0.4323 0.2028
Hs 578T NU7441
3.33
uM
LJP5
 72
hr
 929 2195 3228 0.6801 0.5508
Hs 578T Dactolisib
3.33
uM
LJP5
 72
hr
 929 1177 3228 0.3646 0.1078
Hs 578T NVP-TAE684
3.33
uM
LJP6
 72
hr
 929 1207 3228 0.3739 0.1208
Hs 578T Palbociclib
3.33
uM
LJP6
 72
hr
 929 1645 3228 0.5096 0.3114