LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Canertinib | 0.37 | uM | LJP6 | 72 | hr | 929 | 3123 | 3228 | 0.9675 | 0.9543 |
Hs 578T | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 929 | 2735 | 3228 | 0.8474 | 0.7857 |
Hs 578T | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 929 | 837 | 3228 | 0.2594 | -0.0400 |
Hs 578T | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 929 | 849 | 3228 | 0.2631 | -0.0348 |
Hs 578T | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 929 | 3086 | 3228 | 0.9562 | 0.9385 |
Hs 578T | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 929 | 3087 | 3228 | 0.9563 | 0.9386 |
Hs 578T | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 929 | 3448 | 3228 | 1.0682 | 1.0958 |
Hs 578T | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 2987 | 3228 | 0.9254 | 0.8953 |
Hs 578T | Momelotinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 2528 | 3228 | 0.7833 | 0.6958 |
Hs 578T | Dasatinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 1350 | 3228 | 0.4183 | 0.1832 |
Hs 578T | Dasatinib | 0.37 | uM | LJP6 | 72 | hr | 929 | 1174 | 3228 | 0.3638 | 0.1066 |
Hs 578T | Dovitinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 1674 | 3228 | 0.5186 | 0.3240 |
Hs 578T | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 929 | 3269 | 3228 | 1.0129 | 1.0181 |
Hs 578T | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 3071 | 3228 | 0.9515 | 0.9318 |
Hs 578T | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 929 | 2054 | 3228 | 0.6364 | 0.4894 |
Hs 578T | R406 | 0.37 | uM | LJP6 | 72 | hr | 929 | 2781 | 3228 | 0.8616 | 0.8057 |
Hs 578T | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 929 | 1948 | 3228 | 0.6035 | 0.4432 |
Hs 578T | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 929 | 3155 | 3228 | 0.9774 | 0.9682 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 929 | 1238 | 3228 | 0.3837 | 0.1346 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 929 | 1388 | 3228 | 0.4300 | 0.1996 |
Hs 578T | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 929 | 2192 | 3228 | 0.6790 | 0.5493 |
Hs 578T | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 929 | 2053 | 3228 | 0.6361 | 0.4890 |
Hs 578T | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 929 | 3112 | 3228 | 0.9642 | 0.9497 |
Hs 578T | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 929 | 1158 | 3228 | 0.3587 | 0.0995 |
Hs 578T | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 929 | 2343 | 3228 | 0.7258 | 0.6150 |