LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 513 | 5529 | 10401 | 0.5316 | 0.5073 |
| MCF 10A | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 513 | 1303 | 10401 | 0.1253 | 0.0799 |
| MCF 10A | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 513 | 7272 | 10401 | 0.6992 | 0.6836 |
| MCF 10A | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 513 | 1357 | 10401 | 0.1305 | 0.0853 |
| MCF 10A | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 513 | 1516 | 10401 | 0.1458 | 0.1014 |
| MCF 10A | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 663 | 10401 | 0.0637 | 0.0151 |
| MCF 10A | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 513 | 588 | 10401 | 0.0566 | 0.0076 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 513 | 694 | 10401 | 0.0667 | 0.0183 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 513 | 497 | 10401 | 0.0478 | -0.0016 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 513 | 6771 | 10401 | 0.6510 | 0.6329 |
| MCF 10A | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 513 | 10075 | 10401 | 0.9687 | 0.9671 |
| MCF 10A | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 513 | 10141 | 10401 | 0.9751 | 0.9738 |
| MCF 10A | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 8099 | 10401 | 0.7787 | 0.7672 |
| MCF 10A | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 5846 | 10401 | 0.5621 | 0.5393 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 654 | 10401 | 0.0629 | 0.0143 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 410 | 10401 | 0.0395 | -0.0104 |
| MCF 10A | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 2212 | 10401 | 0.2127 | 0.1718 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 513 | 10017 | 10401 | 0.9631 | 0.9612 |
| MCF 10A | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 626 | 10401 | 0.0602 | 0.0114 |
| MCF 10A | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 2122 | 10401 | 0.2041 | 0.1628 |
| MCF 10A | R406 | 1.11 | uM | LJP6 | 72 | hr | 513 | 7188 | 10401 | 0.6911 | 0.6751 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 513 | 1404 | 10401 | 0.1350 | 0.0901 |
| MCF 10A | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 863 | 10401 | 0.0830 | 0.0354 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 513 | 494 | 10401 | 0.0476 | -0.0019 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 513 | 473 | 10401 | 0.0455 | -0.0040 |