LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 513 6501 10401 0.6250 0.6056
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 513 8387 10401 0.8064 0.7963
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 513 6249 10401 0.6009 0.5801
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 513 10440 10401 1.0037 1.0039
MCF 10A JNK-9L
0.12
uM
LJP6
 72
hr
 513 7616 10401 0.7322 0.7183
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 513 9173 10401 0.8820 0.8759
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 513 8925 10401 0.8581 0.8508
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 513 9904 10401 0.9523 0.9498
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 513 11112 10401 1.0684 1.0720
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 513 7087 10401 0.6814 0.6649
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 513 662 10401 0.0637 0.0151
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 513 690 10401 0.0663 0.0179
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 513 9837 10401 0.9458 0.9430
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 513 766 10401 0.0737 0.0256
MCF 10A Nilotinib
0.12
uM
LJP5
 72
hr
 513 10609 10401 1.0200 1.0210
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 513 10367 10401 0.9968 0.9966
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 513 10405 10401 1.0004 1.0004
MCF 10A Dactolisib
0.12
uM
LJP5
 72
hr
 513 1514 10401 0.1456 0.1013
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 513 3340 10401 0.3212 0.2859
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 513 6252 10401 0.6011 0.5804
MCF 10A PD0325901
0.12
uM
LJP5
 72
hr
 513 842 10401 0.0810 0.0333
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 513 687 10401 0.0661 0.0176
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 513 10571 10401 1.0163 1.0172
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 513 2900 10401 0.2789 0.2414
MCF 10A Pelitinib
0.12
uM
LJP5
 72
hr
 513 811 10401 0.0780 0.0302