LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 513 2639 10401 0.2537 0.2150
MCF 10A PF477736
0.12
uM
LJP5
 72
hr
 513 8819 10401 0.8479 0.8400
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 513 7123 10401 0.6848 0.6685
MCF 10A PHA-665752
0.12
uM
LJP5
 72
hr
 513 10091 10401 0.9703 0.9687
MCF 10A PHA-793887
0.12
uM
LJP6
 72
hr
 513 1086 10401 0.1044 0.0579
MCF 10A PI103
0.12
uM
LJP6
 72
hr
 513 3982 10401 0.3829 0.3509
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 513 10983 10401 1.0560 1.0589
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 513 8468 10401 0.8141 0.8045
MCF 10A QL-XII-47
0.12
uM
LJP6
 72
hr
 513 9154 10401 0.8801 0.8739
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 513 1750 10401 0.1683 0.1251
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 513 1851 10401 0.1780 0.1353
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 513 9976 10401 0.9592 0.9571
MCF 10A Ruxolitinib
0.12
uM
LJP5
 72
hr
 513 10005 10401 0.9619 0.9599
MCF 10A XL147
0.12
uM
LJP5
 72
hr
 513 10166 10401 0.9774 0.9763
MCF 10A Saracatinib
0.12
uM
LJP6
 72
hr
 513 9681 10401 0.9308 0.9272
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 513 2200 10401 0.2116 0.1706
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 513 10290 10401 0.9894 0.9888
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 513 10401 10401 1.0000 1.0000
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 513 10030 10401 0.9644 0.9625
MCF 10A Fedratinib
0.12
uM
LJP5
 72
hr
 513 9869 10401 0.9489 0.9463
MCF 10A TGX221
0.12
uM
LJP5
 72
hr
 513 8843 10401 0.8502 0.8424
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 513 1397 10401 0.1343 0.0894
MCF 10A Torin2
0.12
uM
LJP5
 72
hr
 513 505 10401 0.0486 -0.0008
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 513 1287 10401 0.1238 0.0783
MCF 10A Trametinib
0.12
uM
LJP5
 72
hr
 513 783 10401 0.0753 0.0273