LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A TWS119
0.12
uM
LJP5
 72
hr
 513 10711 10401 1.0298 1.0314
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 513 10275 10401 0.9879 0.9873
MCF 10A Withaferin A
0.12
uM
LJP5
 72
hr
 513 9932 10401 0.9549 0.9526
MCF 10A Withaferin A
0.12
uM
LJP6
 72
hr
 513 9535 10401 0.9168 0.9124
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 513 1471 10401 0.1414 0.0969
MCF 10A WZ3105
0.12
uM
LJP5
 72
hr
 513 759 10401 0.0730 0.0249
MCF 10A XMD11-50
0.12
uM
LJP6
 72
hr
 513 9163 10401 0.8810 0.8748
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 513 7200 10401 0.6923 0.6763
MCF 10A YM 201636
0.12
uM
LJP5
 72
hr
 513 9871 10401 0.9491 0.9464
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 513 5213 10401 0.5012 0.4753
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 513 487 10401 0.0469 -0.0026
MCF 10A Sigma A6730
0.37
uM
LJP5
 72
hr
 513 9545 10401 0.9177 0.9134
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 513 452 10401 0.0435 -0.0062
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 513 995 10401 0.0957 0.0487
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 513 1767 10401 0.1699 0.1268
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 513 7846 10401 0.7543 0.7416
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 513 3341 10401 0.3213 0.2860
MCF 10A AZD8055
0.37
uM
LJP6
 72
hr
 513 1100 10401 0.1058 0.0593
MCF 10A AZD8330
0.37
uM
LJP5
 72
hr
 513 565 10401 0.0544 0.0053
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 513 1313 10401 0.1263 0.0809
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 513 889 10401 0.0855 0.0380
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 513 10154 10401 0.9763 0.9751
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 513 549 10401 0.0528 0.0036
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 513 967 10401 0.0930 0.0459
MCF 10A NVP-AEW541
0.37
uM
LJP5
 72
hr
 513 6000 10401 0.5769 0.5549