LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 513 10700 10401 1.0288 1.0303
MCF 10A PIK-93
0.37
uM
LJP5
 72
hr
 513 10414 10401 1.0012 1.0013
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 513 10145 10401 0.9754 0.9741
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 513 7173 10401 0.6897 0.6736
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 513 476 10401 0.0458 -0.0038
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 513 692 10401 0.0666 0.0181
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 513 2270 10401 0.2183 0.1777
MCF 10A XMD11-85h
0.37
uM
LJP6
 72
hr
 513 9649 10401 0.9277 0.9239
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 513 9226 10401 0.8871 0.8812
MCF 10A WH-4-025
0.37
uM
LJP5
 72
hr
 513 5345 10401 0.5140 0.4887
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 513 8239 10401 0.7921 0.7813
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 513 1414 10401 0.1360 0.0911
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 513 9301 10401 0.8943 0.8888
MCF 10A Buparlisib
0.37
uM
LJP5
 72
hr
 513 5559 10401 0.5345 0.5104
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 513 6485 10401 0.6236 0.6040
MCF 10A Canertinib
0.37
uM
LJP6
 72
hr
 513 737 10401 0.0709 0.0226
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 513 6411 10401 0.6164 0.5965
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 513 685 10401 0.0659 0.0174
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 513 572 10401 0.0550 0.0059
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 513 8716 10401 0.8380 0.8296
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 513 10181 10401 0.9788 0.9777
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 513 10725 10401 1.0312 1.0328
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 513 8666 10401 0.8332 0.8245
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 513 6977 10401 0.6708 0.6537
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 513 792 10401 0.0761 0.0282