LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A CP724714
3.33
uM
LJP5
 72
hr
 513 10064 10401 0.9676 0.9659
MCF 10A CP466722
3.33
uM
LJP5
 72
hr
 513 9517 10401 0.9150 0.9106
MCF 10A Crizotinib
3.33
uM
LJP5
 72
hr
 513 6595 10401 0.6341 0.6151
MCF 10A Momelotinib
3.33
uM
LJP5
 72
hr
 513 4328 10401 0.4162 0.3859
MCF 10A Dasatinib
3.33
uM
LJP5
 72
hr
 513 337 10401 0.0324 -0.0178
MCF 10A Dasatinib
3.33
uM
LJP6
 72
hr
 513 305 10401 0.0293 -0.0211
MCF 10A Dovitinib
3.33
uM
LJP5
 72
hr
 513 1073 10401 0.1032 0.0566
MCF 10A Enzastaurin
3.33
uM
LJP5
 72
hr
 513 9146 10401 0.8793 0.8731
MCF 10A Erlotinib
3.33
uM
LJP5
 72
hr
 513 667 10401 0.0641 0.0155
MCF 10A Foretinib
3.33
uM
LJP5
 72
hr
 513 1147 10401 0.1103 0.0641
MCF 10A R406
3.33
uM
LJP6
 72
hr
 513 5300 10401 0.5096 0.4842
MCF 10A Pictilisib
3.33
uM
LJP6
 72
hr
 513 1104 10401 0.1062 0.0598
MCF 10A Gefitinib
3.33
uM
LJP6
 72
hr
 513 786 10401 0.0756 0.0276
MCF 10A Geldanamycin
3.33
uM
LJP5
 72
hr
 513 389 10401 0.0374 -0.0125
MCF 10A Geldanamycin
3.33
uM
LJP6
 72
hr
 513 393 10401 0.0378 -0.0122
MCF 10A GSK1059615
3.33
uM
LJP5
 72
hr
 513 348 10401 0.0335 -0.0167
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 513 459 10401 0.0441 -0.0055
MCF 10A GSK1904529A
3.33
uM
LJP6
 72
hr
 513 2209 10401 0.2124 0.1715
MCF 10A Omipalisib
3.33
uM
LJP6
 72
hr
 513 431 10401 0.0414 -0.0083
MCF 10A GSK 690693
3.33
uM
LJP5
 72
hr
 513 7222 10401 0.6944 0.6785
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 513 701 10401 0.0674 0.0190
MCF 10A HG-5-113-01
3.33
uM
LJP5
 72
hr
 513 1445 10401 0.1389 0.0942
MCF 10A HG-5-88-01
3.33
uM
LJP6
 72
hr
 513 2412 10401 0.2320 0.1921
MCF 10A Imatinib
3.33
uM
LJP6
 72
hr
 513 11182 10401 1.0751 1.0790
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 513 592 10401 0.0569 0.0080