LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 513 5711 10401 0.5491 0.5257
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 513 3620 10401 0.3481 0.3143
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 513 5692 10401 0.5473 0.5238
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 513 9782 10401 0.9405 0.9374
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 513 3084 10401 0.2965 0.2600
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 513 371 10401 0.0357 -0.0144
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 513 407 10401 0.0391 -0.0108
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 513 6006 10401 0.5775 0.5556
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 513 683 10401 0.0657 0.0172
MCF 10A Nilotinib
3.33
uM
LJP5
 72
hr
 513 10452 10401 1.0050 1.0052
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 513 7959 10401 0.7652 0.7531
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 513 7796 10401 0.7496 0.7366
MCF 10A Dactolisib
3.33
uM
LJP5
 72
hr
 513 967 10401 0.0930 0.0459
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 513 1472 10401 0.1415 0.0970
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 513 3336 10401 0.3207 0.2855
MCF 10A PD0325901
3.33
uM
LJP5
 72
hr
 513 579 10401 0.0557 0.0067
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 513 493 10401 0.0474 -0.0021
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 513 10543 10401 1.0137 1.0144
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 513 1165 10401 0.1120 0.0659
MCF 10A Pelitinib
3.33
uM
LJP5
 72
hr
 513 680 10401 0.0654 0.0169
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 513 761 10401 0.0732 0.0250
MCF 10A PF477736
3.33
uM
LJP5
 72
hr
 513 931 10401 0.0896 0.0423
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 513 668 10401 0.0643 0.0157
MCF 10A PHA-665752
3.33
uM
LJP5
 72
hr
 513 9651 10401 0.9279 0.9242
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 513 511 10401 0.0492 -0.0002