LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3022 | 4156 | 0.7272 | 0.6118 |
MCF7 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3513 | 4156 | 0.8453 | 0.7798 |
MCF7 | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2625 | 4156 | 0.6318 | 0.4760 |
MCF7 | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4481 | 4156 | 1.0782 | 1.1112 |
MCF7 | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2761 | 4156 | 0.6643 | 0.5223 |
MCF7 | JW-7-24-1 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2487 | 4156 | 0.5986 | 0.4288 |
MCF7 | Lapatinib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2964 | 4156 | 0.7132 | 0.5920 |
MCF7 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4794 | 4156 | 1.1535 | 1.2185 |
MCF7 | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4787 | 4156 | 1.1519 | 1.2161 |
MCF7 | Linsitinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3243 | 4156 | 0.7805 | 0.6876 |
MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1380 | 4156 | 0.3322 | 0.0497 |
MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1170 | 4156 | 0.2816 | -0.0223 |
MCF7 | MK2206 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2855 | 4156 | 0.6869 | 0.5545 |
MCF7 | Neratinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3207 | 4156 | 0.7717 | 0.6751 |
MCF7 | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4461 | 4156 | 1.0734 | 1.1045 |
MCF7 | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3999 | 4156 | 0.9622 | 0.9462 |
MCF7 | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4252 | 4156 | 1.0231 | 1.0328 |
MCF7 | Dactolisib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1924 | 4156 | 0.4629 | 0.2358 |
MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2633 | 4156 | 0.6335 | 0.4785 |
MCF7 | Palbociclib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3018 | 4156 | 0.7262 | 0.6104 |
MCF7 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 2959 | 4156 | 0.7120 | 0.5902 |
MCF7 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 2945 | 4156 | 0.7087 | 0.5854 |
MCF7 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4512 | 4156 | 1.0857 | 1.1219 |
MCF7 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4127 | 4156 | 0.9931 | 0.9901 |
MCF7 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4756 | 4156 | 1.1443 | 1.2054 |