LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 PD0325901
0.37
uM
LJP5
 72
hr
 1235 2560 4156 0.6160 0.4535
MCF7 PD0325901
0.37
uM
LJP6
 72
hr
 1235 2320 4156 0.5584 0.3716
MCF7 PD173074
0.37
uM
LJP6
 72
hr
 1235 4506 4156 1.0842 1.1198
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1235 3401 4156 0.8184 0.7416
MCF7 Pelitinib
0.37
uM
LJP5
 72
hr
 1235 4330 4156 1.0420 1.0597
MCF7 PF431396
0.37
uM
LJP5
 72
hr
 1235 1632 4156 0.3927 0.1358
MCF7 PF477736
0.37
uM
LJP5
 72
hr
 1235 2037 4156 0.4901 0.2745
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1235 2418 4156 0.5819 0.4050
MCF7 PHA-665752
0.37
uM
LJP5
 72
hr
 1235 4574 4156 1.1006 1.1432
MCF7 PHA-793887
0.37
uM
LJP6
 72
hr
 1235 1216 4156 0.2927 -0.0064
MCF7 PI103
0.37
uM
LJP6
 72
hr
 1235 1540 4156 0.3706 0.1044
MCF7 PLX-4720
0.37
uM
LJP5
 72
hr
 1235 4133 4156 0.9946 0.9923
MCF7 QL-X-138
0.37
uM
LJP6
 72
hr
 1235 1715 4156 0.4128 0.1644
MCF7 QL-XII-47
0.37
uM
LJP6
 72
hr
 1235 1131 4156 0.2722 -0.0356
MCF7 Radicicol
0.37
uM
LJP5
 72
hr
 1235 1603 4156 0.3857 0.1259
MCF7 Radicicol
0.37
uM
LJP6
 72
hr
 1235 1601 4156 0.3854 0.1254
MCF7 Seliciclib
0.37
uM
LJP5
 72
hr
 1235 3789 4156 0.9117 0.8743
MCF7 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1235 3973 4156 0.9561 0.9375
MCF7 XL147
0.37
uM
LJP5
 72
hr
 1235 4542 4156 1.0929 1.1322
MCF7 Saracatinib
0.37
uM
LJP6
 72
hr
 1235 2013 4156 0.4845 0.2665
MCF7 Selumetinib
0.37
uM
LJP6
 72
hr
 1235 2879 4156 0.6927 0.5627
MCF7 Sirolimus
0.37
uM
LJP6
 72
hr
 1235 2499 4156 0.6013 0.4326
MCF7 Sorafenib
0.37
uM
LJP6
 72
hr
 1235 3908 4156 0.9403 0.9150
MCF7 SU11274
0.37
uM
LJP5
 72
hr
 1235 4597 4156 1.1061 1.1509
MCF7 Fedratinib
0.37
uM
LJP5
 72
hr
 1235 3512 4156 0.8452 0.7797