LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 GSK1059615
0.37
uM
LJP5
72
hr
1235 2598 4156 0.6253 0.4668
MCF7 GSK1059615
0.37
uM
LJP6
72
hr
1235 2508 4156 0.6036 0.4359
MCF7 GSK1904529A
0.37
uM
LJP6
72
hr
1235 1968 4156 0.4736 0.2509
MCF7 Omipalisib
0.37
uM
LJP6
72
hr
1235 1396 4156 0.3361 0.0552
MCF7 GSK 690693
0.37
uM
LJP5
72
hr
1235 2168 4156 0.5218 0.3195
MCF7 GW843682X
0.37
uM
LJP6
72
hr
1235 1517 4156 0.3651 0.0965
MCF7 HG-5-113-01
0.37
uM
LJP5
72
hr
1235 1706 4156 0.4105 0.1611
MCF7 HG-5-88-01
0.37
uM
LJP6
72
hr
1235 2225 4156 0.5355 0.3391
MCF7 Imatinib
0.37
uM
LJP6
72
hr
1235 4629 4156 1.1139 1.1621
MCF7 JNK-9L
0.37
uM
LJP6
72
hr
1235 1370 4156 0.3296 0.0461
MCF7 JW-7-24-1
0.37
uM
LJP6
72
hr
1235 1837 4156 0.4420 0.2060
MCF7 Lapatinib
0.37
uM
LJP6
72
hr
1235 3706 4156 0.8917 0.8459
MCF7 LDN-193189
0.37
uM
LJP5
72
hr
1235 4630 4156 1.1142 1.1625
MCF7 Linifanib
0.37
uM
LJP6
72
hr
1235 4546 4156 1.0938 1.1335
MCF7 Linsitinib
0.37
uM
LJP5
72
hr
1235 2401 4156 0.5778 0.3992
MCF7 Mitoxantrone
0.37
uM
LJP5
72
hr
1235 1487 4156 0.3579 0.0864
MCF7 Mitoxantrone
0.37
uM
LJP6
72
hr
1235 1296 4156 0.3119 0.0209
MCF7 MK2206
0.37
uM
LJP6
72
hr
1235 1620 4156 0.3898 0.1317
MCF7 Neratinib
0.37
uM
LJP5
72
hr
1235 2689 4156 0.6470 0.4977
MCF7 Nilotinib
0.37
uM
LJP5
72
hr
1235 4256 4156 1.0242 1.0344
MCF7 Nintedanib
0.37
uM
LJP6
72
hr
1235 2792 4156 0.6719 0.5331
MCF7 NU7441
0.37
uM
LJP5
72
hr
1235 4230 4156 1.0178 1.0254
MCF7 Dactolisib
0.37
uM
LJP5
72
hr
1235 1679 4156 0.4040 0.1519
MCF7 NVP-TAE684
0.37
uM
LJP6
72
hr
1235 1196 4156 0.2878 -0.0135
MCF7 Palbociclib
0.37
uM
LJP6
72
hr
1235 2124 4156 0.5111 0.3042