LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2598 | 4156 | 0.6253 | 0.4668 |
MCF7 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2508 | 4156 | 0.6036 | 0.4359 |
MCF7 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1968 | 4156 | 0.4736 | 0.2509 |
MCF7 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1396 | 4156 | 0.3361 | 0.0552 |
MCF7 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2168 | 4156 | 0.5218 | 0.3195 |
MCF7 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1517 | 4156 | 0.3651 | 0.0965 |
MCF7 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1706 | 4156 | 0.4105 | 0.1611 |
MCF7 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2225 | 4156 | 0.5355 | 0.3391 |
MCF7 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 4629 | 4156 | 1.1139 | 1.1621 |
MCF7 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1370 | 4156 | 0.3296 | 0.0461 |
MCF7 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1837 | 4156 | 0.4420 | 0.2060 |
MCF7 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 3706 | 4156 | 0.8917 | 0.8459 |
MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4630 | 4156 | 1.1142 | 1.1625 |
MCF7 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 4546 | 4156 | 1.0938 | 1.1335 |
MCF7 | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2401 | 4156 | 0.5778 | 0.3992 |
MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1487 | 4156 | 0.3579 | 0.0864 |
MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1296 | 4156 | 0.3119 | 0.0209 |
MCF7 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1620 | 4156 | 0.3898 | 0.1317 |
MCF7 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2689 | 4156 | 0.6470 | 0.4977 |
MCF7 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4256 | 4156 | 1.0242 | 1.0344 |
MCF7 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2792 | 4156 | 0.6719 | 0.5331 |
MCF7 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4230 | 4156 | 1.0178 | 1.0254 |
MCF7 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1679 | 4156 | 0.4040 | 0.1519 |
MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1196 | 4156 | 0.2878 | -0.0135 |
MCF7 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2124 | 4156 | 0.5111 | 0.3042 |