LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A BI-2536
3.33
uM
LJP6
 72
hr
 513 740 10401 0.0711 0.0229
MCF 10A BMS345541
3.33
uM
LJP6
 72
hr
 513 9529 10401 0.9162 0.9119
MCF 10A SNS-032
3.33
uM
LJP6
 72
hr
 513 488 10401 0.0469 -0.0026
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 513 603 10401 0.0580 0.0091
MCF 10A NVP-AEW541
3.33
uM
LJP5
 72
hr
 513 3020 10401 0.2904 0.2535
MCF 10A SB590885
3.33
uM
LJP5
 72
hr
 513 9274 10401 0.8917 0.8860
MCF 10A PIK-93
3.33
uM
LJP5
 72
hr
 513 5421 10401 0.5213 0.4964
MCF 10A KIN001-043
3.33
uM
LJP6
 72
hr
 513 6085 10401 0.5850 0.5635
MCF 10A Alpelisib
3.33
uM
LJP5
 72
hr
 513 4552 10401 0.4377 0.4085
MCF 10A Luminespib
3.33
uM
LJP5
 72
hr
 513 492 10401 0.0473 -0.0021
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 513 351 10401 0.0338 -0.0164
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 513 1101 10401 0.1059 0.0595
MCF 10A XMD11-85h
3.33
uM
LJP6
 72
hr
 513 8668 10401 0.8334 0.8248
MCF 10A HG-6-64-01
3.33
uM
LJP6
 72
hr
 513 1652 10401 0.1589 0.1152
MCF 10A WH-4-025
3.33
uM
LJP5
 72
hr
 513 1148 10401 0.1104 0.0642
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 513 4150 10401 0.3990 0.3678
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 513 1297 10401 0.1247 0.0793
MCF 10A Brivanib
3.33
uM
LJP5
 72
hr
 513 4641 10401 0.4462 0.4175
MCF 10A Buparlisib
3.33
uM
LJP5
 72
hr
 513 386 10401 0.0371 -0.0129
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 513 1326 10401 0.1275 0.0822
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 513 694 10401 0.0668 0.0183
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 513 450 10401 0.0433 -0.0064
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 513 666 10401 0.0640 0.0154
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 513 484 10401 0.0465 -0.0030
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 513 6115 10401 0.5880 0.5666