LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A TGX221
1.11
uM
LJP5
 72
hr
 513 8824 10401 0.8484 0.8406
MCF 10A Torin1
1.11
uM
LJP6
 72
hr
 513 1111 10401 0.1069 0.0605
MCF 10A Torin2
1.11
uM
LJP5
 72
hr
 513 484 10401 0.0465 -0.0030
MCF 10A Tozasertib
1.11
uM
LJP5
 72
hr
 513 1080 10401 0.1038 0.0573
MCF 10A Trametinib
1.11
uM
LJP5
 72
hr
 513 880 10401 0.0846 0.0371
MCF 10A TWS119
1.11
uM
LJP5
 72
hr
 513 10220 10401 0.9826 0.9817
MCF 10A Vemurafenib
1.11
uM
LJP5
 72
hr
 513 8358 10401 0.8036 0.7934
MCF 10A Withaferin A
1.11
uM
LJP5
 72
hr
 513 446 10401 0.0429 -0.0067
MCF 10A Withaferin A
1.11
uM
LJP6
 72
hr
 513 502 10401 0.0483 -0.0011
MCF 10A WYE-125132
1.11
uM
LJP6
 72
hr
 513 1041 10401 0.1001 0.0534
MCF 10A WZ3105
1.11
uM
LJP5
 72
hr
 513 630 10401 0.0606 0.0118
MCF 10A XMD11-50
1.11
uM
LJP6
 72
hr
 513 4147 10401 0.3988 0.3676
MCF 10A Y39983
1.11
uM
LJP6
 72
hr
 513 7021 10401 0.6751 0.6582
MCF 10A YM 201636
1.11
uM
LJP5
 72
hr
 513 6499 10401 0.6249 0.6054
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 513 2117 10401 0.2036 0.1622
MCF 10A Afatinib
3.33
uM
LJP6
 72
hr
 513 525 10401 0.0505 0.0012
MCF 10A Sigma A6730
3.33
uM
LJP5
 72
hr
 513 8297 10401 0.7978 0.7873
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 513 505 10401 0.0486 -0.0008
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 513 665 10401 0.0640 0.0154
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 513 704 10401 0.0677 0.0193
MCF 10A AZD-6482
3.33
uM
LJP5
 72
hr
 513 4932 10401 0.4742 0.4469
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 513 936 10401 0.0901 0.0428
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 513 927 10401 0.0892 0.0419
MCF 10A AZD8330
3.33
uM
LJP5
 72
hr
 513 652 10401 0.0627 0.0140
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 513 1376 10401 0.1323 0.0872