LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 513 | 721 | 10401 | 0.0694 | 0.0210 |
| MCF 10A | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 513 | 535 | 10401 | 0.0515 | 0.0023 |
| MCF 10A | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 513 | 10484 | 10401 | 1.0080 | 1.0084 |
| MCF 10A | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 513 | 1543 | 10401 | 0.1484 | 0.1042 |
| MCF 10A | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 767 | 10401 | 0.0737 | 0.0257 |
| MCF 10A | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 513 | 853 | 10401 | 0.0820 | 0.0343 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 513 | 3600 | 10401 | 0.3462 | 0.3122 |
| MCF 10A | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 513 | 1722 | 10401 | 0.1656 | 0.1223 |
| MCF 10A | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 513 | 9599 | 10401 | 0.9229 | 0.9189 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 513 | 611 | 10401 | 0.0587 | 0.0099 |
| MCF 10A | PI103 | 1.11 | uM | LJP6 | 72 | hr | 513 | 1061 | 10401 | 0.1020 | 0.0554 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 513 | 11521 | 10401 | 1.1077 | 1.1133 |
| MCF 10A | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 513 | 4231 | 10401 | 0.4068 | 0.3760 |
| MCF 10A | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 513 | 2267 | 10401 | 0.2180 | 0.1774 |
| MCF 10A | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 513 | 720 | 10401 | 0.0692 | 0.0209 |
| MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 513 | 742 | 10401 | 0.0713 | 0.0231 |
| MCF 10A | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 513 | 9610 | 10401 | 0.9240 | 0.9201 |
| MCF 10A | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 8960 | 10401 | 0.8614 | 0.8543 |
| MCF 10A | XL147 | 1.11 | uM | LJP5 | 72 | hr | 513 | 9726 | 10401 | 0.9352 | 0.9318 |
| MCF 10A | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 4140 | 10401 | 0.3980 | 0.3668 |
| MCF 10A | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 513 | 1235 | 10401 | 0.1188 | 0.0731 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 513 | 10098 | 10401 | 0.9709 | 0.9694 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 513 | 10318 | 10401 | 0.9921 | 0.9917 |
| MCF 10A | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 513 | 7883 | 10401 | 0.7580 | 0.7454 |
| MCF 10A | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 7786 | 10401 | 0.7486 | 0.7356 |