LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Selumetinib
10.0
uM
LJP6
 72
hr
 513 900 10401 0.0866 0.0391
MCF 10A Sirolimus
10.0
uM
LJP6
 72
hr
 513 9940 10401 0.9557 0.9534
MCF 10A Sorafenib
10.0
uM
LJP6
 72
hr
 513 5955 10401 0.5726 0.5504
MCF 10A SU11274
10.0
uM
LJP5
 72
hr
 513 2602 10401 0.2502 0.2112
MCF 10A Fedratinib
10.0
uM
LJP5
 72
hr
 513 570 10401 0.0549 0.0058
MCF 10A TGX221
10.0
uM
LJP5
 72
hr
 513 7674 10401 0.7378 0.7242
MCF 10A Torin1
10.0
uM
LJP6
 72
hr
 513 863 10401 0.0830 0.0354
MCF 10A Torin2
10.0
uM
LJP5
 72
hr
 513 484 10401 0.0465 -0.0030
MCF 10A Tozasertib
10.0
uM
LJP5
 72
hr
 513 824 10401 0.0792 0.0314
MCF 10A Trametinib
10.0
uM
LJP5
 72
hr
 513 1020 10401 0.0981 0.0513
MCF 10A TWS119
10.0
uM
LJP5
 72
hr
 513 385 10401 0.0371 -0.0129
MCF 10A Vemurafenib
10.0
uM
LJP5
 72
hr
 513 1903 10401 0.1830 0.1406
MCF 10A Withaferin A
10.0
uM
LJP5
 72
hr
 513 321 10401 0.0309 -0.0194
MCF 10A Withaferin A
10.0
uM
LJP6
 72
hr
 513 325 10401 0.0312 -0.0191
MCF 10A WYE-125132
10.0
uM
LJP6
 72
hr
 513 882 10401 0.0848 0.0373
MCF 10A WZ3105
10.0
uM
LJP5
 72
hr
 513 525 10401 0.0505 0.0012
MCF 10A XMD11-50
10.0
uM
LJP6
 72
hr
 513 931 10401 0.0895 0.0423
MCF 10A Y39983
10.0
uM
LJP6
 72
hr
 513 1133 10401 0.1090 0.0627
MCF 10A YM 201636
10.0
uM
LJP5
 72
hr
 513 1389 10401 0.1336 0.0886
MCF 10A ZSTK474
10.0
uM
LJP6
 72
hr
 513 1292 10401 0.1242 0.0787
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1235 2830 4156 0.6811 0.5462
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1235 3330 4156 0.8014 0.7174
MCF7 Alvocidib
0.04
uM
LJP6
 72
hr
 1235 1126 4156 0.2709 -0.0375
MCF7 AT-7519
0.04
uM
LJP6
 72
hr
 1235 3560 4156 0.8567 0.7961
MCF7 AZD 5438
0.04
uM
LJP6
 72
hr
 1235 3569 4156 0.8589 0.7992