LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 AZD-6482
0.04
uM
LJP5
72
hr
1235 4799 4156 1.1547 1.2202
MCF7 AZD7762
0.04
uM
LJP6
72
hr
1235 1904 4156 0.4581 0.2289
MCF7 AZD8055
0.04
uM
LJP6
72
hr
1235 1307 4156 0.3146 0.0247
MCF7 AZD8330
0.04
uM
LJP5
72
hr
1235 1989 4156 0.4786 0.2580
MCF7 Barasertib
0.04
uM
LJP5
72
hr
1235 1732 4156 0.4168 0.1701
MCF7 BI-2536
0.04
uM
LJP6
72
hr
1235 1523 4156 0.3664 0.0985
MCF7 BMS345541
0.04
uM
LJP6
72
hr
1235 4482 4156 1.0786 1.1118
MCF7 SNS-032
0.04
uM
LJP6
72
hr
1235 726 4156 0.1748 -0.1743
MCF7 GDC-0980
0.04
uM
LJP5
72
hr
1235 1394 4156 0.3355 0.0544
MCF7 NVP-AEW541
0.04
uM
LJP5
72
hr
1235 4234 4156 1.0187 1.0266
MCF7 SB590885
0.04
uM
LJP5
72
hr
1235 4382 4156 1.0543 1.0773
MCF7 PIK-93
0.04
uM
LJP5
72
hr
1235 4925 4156 1.1851 1.2633
MCF7 KIN001-043
0.04
uM
LJP6
72
hr
1235 3928 4156 0.9452 0.9220
MCF7 Alpelisib
0.04
uM
LJP5
72
hr
1235 3948 4156 0.9500 0.9288
MCF7 Luminespib
0.04
uM
LJP5
72
hr
1235 1452 4156 0.3494 0.0743
MCF7 A443654
0.04
uM
LJP6
72
hr
1235 1024 4156 0.2464 -0.0724
MCF7 OSI-027
0.04
uM
LJP6
72
hr
1235 3766 4156 0.9063 0.8667
MCF7 XMD11-85h
0.04
uM
LJP6
72
hr
1235 3319 4156 0.7986 0.7134
MCF7 HG-6-64-01
0.04
uM
LJP6
72
hr
1235 4834 4156 1.1631 1.2321
MCF7 WH-4-025
0.04
uM
LJP5
72
hr
1235 4203 4156 1.0113 1.0160
MCF7 WZ-4-145
0.04
uM
LJP6
72
hr
1235 3090 4156 0.7436 0.6352
MCF7 XMD16-144
0.04
uM
LJP5
72
hr
1235 1716 4156 0.4130 0.1647
MCF7 Brivanib
0.04
uM
LJP5
72
hr
1235 3555 4156 0.8554 0.7942
MCF7 Buparlisib
0.04
uM
LJP5
72
hr
1235 3877 4156 0.9330 0.9047
MCF7 BX-912
0.04
uM
LJP5
72
hr
1235 3458 4156 0.8322 0.7612