LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4799 | 4156 | 1.1547 | 1.2202 |
MCF7 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1904 | 4156 | 0.4581 | 0.2289 |
MCF7 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1307 | 4156 | 0.3146 | 0.0247 |
MCF7 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1989 | 4156 | 0.4786 | 0.2580 |
MCF7 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1732 | 4156 | 0.4168 | 0.1701 |
MCF7 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1523 | 4156 | 0.3664 | 0.0985 |
MCF7 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4482 | 4156 | 1.0786 | 1.1118 |
MCF7 | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 726 | 4156 | 0.1748 | -0.1743 |
MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1394 | 4156 | 0.3355 | 0.0544 |
MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4234 | 4156 | 1.0187 | 1.0266 |
MCF7 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4382 | 4156 | 1.0543 | 1.0773 |
MCF7 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4925 | 4156 | 1.1851 | 1.2633 |
MCF7 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3928 | 4156 | 0.9452 | 0.9220 |
MCF7 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3948 | 4156 | 0.9500 | 0.9288 |
MCF7 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1452 | 4156 | 0.3494 | 0.0743 |
MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1024 | 4156 | 0.2464 | -0.0724 |
MCF7 | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3766 | 4156 | 0.9063 | 0.8667 |
MCF7 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3319 | 4156 | 0.7986 | 0.7134 |
MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 4834 | 4156 | 1.1631 | 1.2321 |
MCF7 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4203 | 4156 | 1.0113 | 1.0160 |
MCF7 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3090 | 4156 | 0.7436 | 0.6352 |
MCF7 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1716 | 4156 | 0.4130 | 0.1647 |
MCF7 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3555 | 4156 | 0.8554 | 0.7942 |
MCF7 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3877 | 4156 | 0.9330 | 0.9047 |
MCF7 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3458 | 4156 | 0.8322 | 0.7612 |