LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3301 4156 0.7944 0.7074
MCF7 Sigma A6730
0.37
uM
LJP5
 72
hr
 1235 3167 4156 0.7621 0.6615
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1235 694 4156 0.1671 -0.1852
MCF7 AT-7519
0.37
uM
LJP6
 72
hr
 1235 834 4156 0.2008 -0.1373
MCF7 AZD 5438
0.37
uM
LJP6
 72
hr
 1235 1345 4156 0.3238 0.0378
MCF7 AZD-6482
0.37
uM
LJP5
 72
hr
 1235 4040 4156 0.9721 0.9603
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1235 1544 4156 0.3715 0.1057
MCF7 AZD8055
0.37
uM
LJP6
 72
hr
 1235 1289 4156 0.3101 0.0184
MCF7 AZD8330
0.37
uM
LJP5
 72
hr
 1235 2089 4156 0.5028 0.2925
MCF7 Barasertib
0.37
uM
LJP5
 72
hr
 1235 1618 4156 0.3894 0.1311
MCF7 BI-2536
0.37
uM
LJP6
 72
hr
 1235 1463 4156 0.3522 0.0782
MCF7 BMS345541
0.37
uM
LJP6
 72
hr
 1235 3766 4156 0.9062 0.8665
MCF7 SNS-032
0.37
uM
LJP6
 72
hr
 1235 574 4156 0.1383 -0.2262
MCF7 GDC-0980
0.37
uM
LJP5
 72
hr
 1235 1114 4156 0.2681 -0.0414
MCF7 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1235 2543 4156 0.6119 0.4477
MCF7 SB590885
0.37
uM
LJP5
 72
hr
 1235 4641 4156 1.1168 1.1662
MCF7 PIK-93
0.37
uM
LJP5
 72
hr
 1235 5022 4156 1.2085 1.2967
MCF7 KIN001-043
0.37
uM
LJP6
 72
hr
 1235 3856 4156 0.9278 0.8972
MCF7 Alpelisib
0.37
uM
LJP5
 72
hr
 1235 2680 4156 0.6450 0.4948
MCF7 Luminespib
0.37
uM
LJP5
 72
hr
 1235 1473 4156 0.3544 0.0814
MCF7 A443654
0.37
uM
LJP6
 72
hr
 1235 838 4156 0.2017 -0.1359
MCF7 OSI-027
0.37
uM
LJP6
 72
hr
 1235 2071 4156 0.4983 0.2861
MCF7 XMD11-85h
0.37
uM
LJP6
 72
hr
 1235 3599 4156 0.8661 0.8095
MCF7 HG-6-64-01
0.37
uM
LJP6
 72
hr
 1235 3989 4156 0.9599 0.9430
MCF7 WH-4-025
0.37
uM
LJP5
 72
hr
 1235 1967 4156 0.4734 0.2507